- Page 1: Autologous Bone Marrow Transplantat
- Page 5 and 6: Autologous Bone Marrow Transplantat
- Page 7: To our colleagues, Drs. R. Lee Clar
- Page 10 and 11: via ABMT Autologous Bone Marrow Tra
- Page 12 and 13: X ABMT Pharmacological Manipulation
- Page 14 and 15: XII ABMT C. INTERNATIONAL RANDOMIZE
- Page 16 and 17: xiu ABMT Session IV - Breast Cancer
- Page 18 and 19: xui ABMT Panel Discussion: Session
- Page 20 and 21: xuiii ABMT Effect of Interleukin 2
- Page 23: Acknowledgments The publication of
- Page 28 and 29: 4 AML in First Remission used in pa
- Page 30 and 31: 6 AML in First Remission i 40- < 3
- Page 33 and 34: BAVC Regimen and Autologous Bone Ma
- Page 35 and 36: BAVC + ABMT in Patients With AML in
- Page 37 and 38: BAVC + ABMT in Patients With AML in
- Page 39 and 40: Use of Bone Marrow Incubated With M
- Page 41 and 42: Purged ABMT in CR of Acute Leukemia
- Page 43 and 44: Purged ABMT in CR of Acute Leukemia
- Page 45 and 46: Purged ABMT in CR of Acute Leukemia
- Page 47 and 48: Autologous Transplantation of Unpur
- Page 49 and 50: First-Remission Autograft forAML 25
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- Page 53: First-Remission Autograft for AML 2
- Page 56 and 57: 32 Transplantation in CRI AML Of 24
- Page 59 and 60: Autologous Bone Marrow Transplantat
- Page 61 and 62: ABMT in ALL 37 Table 1. Patient Cha
- Page 63 and 64: ABMT in ALL 39 CRj (N. 16) CRJ+CRJ
- Page 65 and 66: ABMT in ALL 41 (46.5% for ALL and 4
- Page 67 and 68: Studies of High-Dose Intensificatio
- Page 69 and 70: ABMTinCRl 45 Induction V A D C- V A
- Page 71: ABMTin CRI 47 DFS rate for the CBV-
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50 Panel Discussion: Session IA the
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52 Panel Discussion: Session IA DR.
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A Study Design to Determine the Rol
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ABMT In CR2 57 CR INVERSION: 2/22 -
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Autologous Bone Marrow Transplantat
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ABMT in Acute Nonlymphocytic Leukem
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ABMT in Acute Nonlymphocytic Leukem
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ABMT in Acute Nonlymphocytic Leukem
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ABMT in Acute Nonlymphocytic Leukem
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Transplantation Trial With Marrow T
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ABMTin AML With Monoclonal Antibodi
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ABMT in AML With Monoclonal Antibod
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ABMT in AML With Monoclonal Antibod
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ABMT in AML With Monoclonal Antibod
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Chemopurging of Autologous Bone Mar
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Mafosfamlde Purging in Leukemia 81
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Mafosfamide Purging in Leukemia 83
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Mafosfamide Purging in Leukemia 85
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Mafosfamide Purging in Leukemia 87
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90 ABMT in CR2 Pediatric ALL Immuno
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92 ABMT in CR2 Pediatric ALL first
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94 Ex Vivo Marrow Purging with marr
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96 Ex Vivo Marrow Purging BONE MARR
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98 Ex Vivo Marrow Purging reflect t
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700 Conditioning Regimens in AML cy
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102 Conditioning Regimens in AML Ta
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Double CInpurged Autologous Bone Ma
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Double Unpurged ABMT in Leukemias 1
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Double (Jnpurged ABMT in Leukemias
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Double Autografting as Potential Cu
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Double Autografting in Acute Leukem
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Double Autografting in Acute Leukem
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Double Autografting in Acute Leukem
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Hematopoietic Recovery After Bone M
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Recovery After 4-Hydroperoxycycloph
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Recovery After 4-Hydroperoxycycloph
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126 Panel Discussion: Session IB DR
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128 Panel Discussion: Session IB 18
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IC. Leukemia Purging/Detection of M
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134 Magnetic Separation of Marrow C
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136 Magnetic Separation of Marrow C
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Ol O) < c « .o. >» o T3 c « =5
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M I M ! CM CO CO CO CO LO M M CO CO
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742 Magnetic Separation of Marrow C
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144 Chemopurging leukemic (ALL) pat
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746 Chemopurging isoeffect. On the
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148 Chemopurging Table 4. Ex Vivo P
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750 Chemopurging 5. Kaizer H, Stuar
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152 Merocyanine 540 Marrow Decontam
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754 Merocyanine 540 Marrow Decontam
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756 Merocyanine 540 Marrow Decontam
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758 CALLA-Negatiue Clonogenic B-Cel
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160 CALLA-Negatiue Clonogenic B-Cel
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Acetaldophosphamide—A New Stable
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Acetaldophosphamide Ex Vivo Chemoth
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Acetaldophosphamide Ex Vivo Chemoth
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Acetaldophosphamide Ex Vivo Chemoth
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172 Detecting Residual Disease in B
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174 Detecting Residual Disease in B
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Pharmacological Manipulation to Rev
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Pharmacological Manipulation and Pu
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Pharmacological Manipulation and Pu
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Pharmacological Manipulation and Pu
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Pharmacological Manipulation and Pu
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Transient Restoration of Partial Ph
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CO o o o o o •o c co CD È >•!
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CML Chronic Phase Autografting 193
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Mitoxantrone, Cytarabine, and Melph
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CML Blast Crisis Autografting 197 c
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200 Autografting in Chronic Granulo
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202 Autografting in Chronic Granulo
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Autologous Bone Marrow Transplantat
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IIA. Hodgkin's Disease
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210 ABMTin Hodgkin's Disease Analys
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212 ABMTin Hodgkin's Disease CR n =
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214 ABMTin Hodgkin's Disease Postmo
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216 ABMTin Hodgkin's Disease progno
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218 CBV and ABMT in Hodgkin s Disea
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220 CBV and ABMT in Hodgkin s Disea
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High-Dose Chemotherapy and Autologo
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Chemotherapy andABMT in Hodgkin's D
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Chemotherapy and ABMTin Hodgkin's D
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Chemotherapy andABMTin Hodgkin s Di
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Treating Advanced Hodgkin's Disease
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ABMT for Advanced Hodgkin's Disease
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ABMT for Advanced Hodgkin's Disease
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238 Panel Discussion: Session IIA D
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240 Panel Discussion: Session IIA D
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Recent Results With Salvage Chemoth
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Salvage Chemotherapy for Lymphoma 2
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Salvage Chemotherapy for Lymphoma 2
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250 ABMTin Burkitt's Lymphoma (8-10
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252 ABMT in Burkitt's Lymphoma intr
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254 ABMTin Burkitts Lymphoma Table
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256 ABMT in Burkitt's Lymphoma rela
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258 ABMT in Burkitt's Lymphoma DISC
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260 ABMTin Burkitts Lymphoma restri
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Biology and Therapy of Multiple Mye
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Myeloma Biology and Therapy 265 onl
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Myeloma Biology and Therapy 267 res
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Bone Marrow Transplantation in Rela
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(S E o I 9*1 0 ü 41 O) CD ~ i: O)
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BMT in Relapsed Diffuse Large Cell
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Treatment of Malignant Lymphoma at
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Transplantation for Malignant Lymph
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280 ABMT Timing in Lymphoma produce
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0) O) .2 '55 o c O) o o Q. c o + +
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284 ABMT Timing in Lymphoma ABMT on
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286 ABMT Timing in Lymphoma abdomin
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« "5 a o « £ a> Z aT in O Q « O
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290 ABMT Timing in Lymphoma Role of
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292 ABMT Timing in Lymphoma inducti
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294 ABMT Timing in Lymphoma Clift R
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Treatment Strategies for Advanced A
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Treatment Strategies for NHL 299 Su
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« E BS « oc c 4> E ai O c CD e 0)
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Treatment Strategies for NHL 303 So
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Treatment Strategies for NHL 305 pa
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Non-Hodgkin's Lymphoma S. Gulati an
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Panel Discussion: Session IIB 309 i
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An International Randomized Study o
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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Proposed International Adult Lympho
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336 International NHL Trial THEORET
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338 International NHL Trial RELAPSE
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340 International NHL Trial ANALYSI
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342 International NHL Trial The ste
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344 Panel Discussion: Session IIC d
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Chemoimmunoseparation of T Lymphoma
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Chemoimmunoseparation of T Lymphoma
- Page 375 and 376:
Using a Liquid Cell Culture Assay t
- Page 377 and 378:
Burkitt's Lymphoma Purging Assay 35
- Page 379 and 380:
Burkitt's Lymphoma Purging Assay 35
- Page 381 and 382:
Burkitt's Lymphoma Purging Assay 35
- Page 383 and 384:
Comparative Efficiency of an Immuno
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Purging Methods in Burkitt's Lympho
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Purging Methods in Burkitt's Lympho
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Susceptibility of Lymphoid Malignan
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Leukemia Cell Sensitioity to Immuno
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Leukemia Cell Sensitivity to Immuno
- Page 395 and 396:
Lymphoma: Purging and Detecting K.
- Page 397:
III. Neuroblastoma
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376 ABMT for Neuroblastoma TOXICITY
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378 ABMT for Neuroblastoma 100 Befo
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380 ABMTfor Neuroblastoma modificat
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382 ABMTfor Neuroblastoma Naval Med
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384 ABMT in Metastatic Neuroblastom
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386 ABMT in Metastatic Neuroblastom
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388 ABMT in Metastatic Neuroblastom
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390 ABMT in Metastatic Neuroblastom
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High-Dose Therapy and Unpurged Bone
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Unpurged ABMTfor Neuroblastoma 395
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(Jnpurged ABMT for Neuroblastoma 39
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Unpurged ABMT for Neuroblastoma 399
- Page 426 and 427:
402 High-Dose Melphalan in Neurobla
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404 High-Dose Melphalan in Neurobla
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Bone Marrow Transplantation in an C
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ABMT in 65 Patients With Neuroblast
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ABMT in 65 Patients With Neuroblast
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ABMT in 65 Patients With Neuroblast
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ABMTin 65 Patients With Neuroblasto
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ABMTin 65 Patients With Neuroblasto
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420 ABMT in Neuroblastoma Group 2
- Page 446 and 447:
422 ABMT in Neuroblastoma RESULTS A
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Transplantation for Neuroblastoma U
- Page 451 and 452:
Purged Marrow Engraftment in Neurob
- Page 453 and 454:
Purged Marrow Engraftment in Neurob
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Purged Marrow Engraftment in Neurob
- Page 458 and 459:
s o o o i o i - w n . t t i s T - T
- Page 460 and 461:
436 Digital Image Analysis System a
- Page 462 and 463:
438 Digital Image Analysis System T
- Page 464 and 465:
440 Digital Image Analysis System u
- Page 467 and 468:
Eliminating Burkitt's Cells From Ex
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Immunomagnetic Purging ofBurkitt's
- Page 471 and 472:
Immunomagnetic Purging ofBurkitt's
- Page 473 and 474:
Neuroblastoma T. Philip and C. P. R
- Page 475 and 476:
Panel Discussion: Session 111 451 w
- Page 477:
IV. Breast Cancer
- Page 480 and 481:
456 High-Dose Chemotherapy and ABMT
- Page 482 and 483:
458 High-Dose Chemotherapy and ABMT
- Page 484 and 485:
460 High-Dose Chemotherapy and ABMT
- Page 486 and 487:
462 High-Dose Chemotherapy and ABMT
- Page 489 and 490:
Strategies in the Treatment of Brea
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Treatment Strategies in Breast Canc
- Page 493 and 494:
Treatment Strategies in Breast Canc
- Page 495 and 496:
Treatment Strategies in Breast Canc
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Treatment Strategies in Breast Canc
- Page 499 and 500:
Phase I and II Studies of High-Dose
- Page 501 and 502:
a « O 75 o c Ü co s g c .2 — o
- Page 503 and 504:
+ O CM CD CM CO CO O O CM O CM CM 8
- Page 505 and 506:
High-Dose Chemotherapy and Autologo
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High-Dose Therapy and ABMT in Breas
- Page 509 and 510:
Immunodetection of Breast Carcinoma
- Page 511:
Immunodetection of Breast Carcinoma
- Page 514 and 515:
490 ABMTfor Breast Cancer initial s
- Page 516 and 517:
492 ABMT for Breast Cancer agent gr
- Page 518 and 519:
494 ABMT for Breast Cancer approach
- Page 521 and 522:
Detection of Occult Breast Cancer C
- Page 523 and 524:
Occult Breast Cancer Cells in Marro
- Page 525 and 526:
Occult Breast Cancer Cells in Marro
- Page 527 and 528:
Breast Cancer E. Frei III and R. Ba
- Page 529 and 530:
Panel Discussion: Session IV 505 DR
- Page 531:
V. Lung Cancer
- Page 534 and 535:
570 Tumor Cell Detection MATERIAL A
- Page 536 and 537:
512 Tumor Cell Detection Table 3. I
- Page 539 and 540:
High-Dose Etoposide and Cisplatin W
- Page 541 and 542:
Etoposide and Cisplatin for Lung Ca
- Page 543 and 544:
Etoposide and Cisplatin for Lung Ca
- Page 545:
Etoposide and Cisplatin for Lung Ca
- Page 548 and 549:
524 Panel Discussion: Session V to
- Page 550 and 551:
526 Panel Discussion: Session V sma
- Page 553:
VI. Melanoma/Sarcoma/Carcinoma
- Page 556 and 557:
532 ABMT in Melanoma chemotherapy a
- Page 558 and 559:
534 ABMT in Melanoma Table 2. Effec
- Page 560 and 561:
536 ABMT in Melanoma with either si
- Page 562 and 563:
538 Panel Discussion: Session VI ca
- Page 564 and 565:
540 Panel Discussion: Session VI sa
- Page 567 and 568:
Intensive Monochemotherapy With Car
- Page 569 and 570:
Carmustine and ABMTfor Malignant Gl
- Page 571:
Carmustine andABMTfor Malignant Gli
- Page 574 and 575:
550 High-Dose Carmustine and Transp
- Page 576 and 577:
552 High-Dose Carmustine and Transp
- Page 578 and 579:
554 High-Dose Carmustine and Transp
- Page 580 and 581:
556 High-Dose Carmustine and Transp
- Page 582 and 583:
558 High-Dose Therapy of CHS Glioma
- Page 584 and 585:
560 High-Dose Therapy of CHS Glioma
- Page 586 and 587:
562 High-Dose Therapy of CHS Glioma
- Page 589 and 590:
Brain Cancer S. Wolff and G. Herzig
- Page 591:
Panel Discussion: Session VII 567 D
- Page 595 and 596:
Intensification Regimens for Autolo
- Page 597 and 598:
Clinical Intensification Regimens f
- Page 599 and 600:
c « O) o in CM -r 1 •«t 00 i -
- Page 601 and 602:
Clinical Intensification Regimens f
- Page 603:
Clinical Intensification Regimens f
- Page 606 and 607:
582 Busulfan + Cyclophosphamide in
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Busulfan + Cyclophosphamide in Chil
- Page 610 and 611:
586 Busulfan + Cyclophosphamide in
- Page 612 and 613:
588 Busulfan + Cyclophosphamide in
- Page 614 and 615:
590 Intensive use of Carmustine Pul
- Page 617 and 618:
A Phase II Study of a New Cytoreduc
- Page 619 and 620:
BEAM: Cytoreductiue Regimen for Lym
- Page 621 and 622:
BEAM: Cytoreductiue Regimen for Lym
- Page 623 and 624:
BEAM: Cytoreductlue Regimen for Lym
- Page 625 and 626:
Total Body Irradiation, High-Dose C
- Page 627 and 628:
Total Body Irradiation, Cytarabine,
- Page 629 and 630:
New Regimens K. Antman and M. Syman
- Page 631:
IX. Supportive Therapy
- Page 634 and 635:
670 Herpesvirus Infections Table 1.
- Page 636 and 637:
612 Herpesvirus Infections Table 3.
- Page 639 and 640:
Autologous Blood Stem Cell Transpla
- Page 641 and 642:
Peripheral Stem Cell Transplantatio
- Page 643 and 644:
Peripheral Stem Cell Transplantatio
- Page 645 and 646:
Peripheral Stem Cell Transplantatio
- Page 647 and 648:
Peripheral Stem Cell Transplantatio
- Page 649 and 650:
a c CO TO O O S E => CO "O CO i- t
- Page 651 and 652:
3 w •o « C C o ü ü CD < , o E
- Page 653 and 654:
Peripheral Stem Cell Transplantatio
- Page 655 and 656:
Peripheral Stem Cell Transplantatio
- Page 657 and 658:
Toxic Deaths After Autologous Bone
- Page 659 and 660:
Toxic Deaths in ABMT 635 RESULTS Fi
- Page 661 and 662:
Toxic Deaths in ABMT 63 7 Patient/
- Page 663 and 664:
Infectious Complications of Autolog
- Page 665 and 666:
Infectious Complications of ABMT Ta
- Page 667 and 668:
Infectious Complications ofABMT 643
- Page 669:
Infectious Complications ofABMT 645
- Page 672 and 673:
648 Infections in ABMT MATERIAL AND
- Page 674 and 675:
650 Infections in ABMT Category Tab
- Page 676 and 677:
652 Infections in ABMT been found,
- Page 678 and 679:
654 Antibiotics in Cancer Patients
- Page 680 and 681:
656 Antibiotics in Cancer Patients
- Page 683 and 684:
The Empiric Use of Amphotericin B f
- Page 685 and 686:
Amphotericin B for Neutropenie Feue
- Page 687 and 688:
Amphotericin B for Neutropenie Feve
- Page 689 and 690:
The Role of Intravenous Immune Glob
- Page 691 and 692:
Mg in ABMT 667 broken down; antigen
- Page 693 and 694:
The Possible Therapeutic Value of N
- Page 695 and 696:
Natural Killer Cells and Transplant
- Page 697:
Natural Killer Cells and Transplant
- Page 700:
676 Transplantation of Circulating
- Page 703:
Transplantation of Circulating Stem
- Page 706 and 707:
682 Peripheral Stem Cell Transplant
- Page 708 and 709:
684 Peripheral Stem Cell Transplant
- Page 711 and 712:
Autologous Transplantation Using Pe
- Page 713 and 714:
Peripheral Blood Stem Cell Transpla
- Page 715 and 716:
Peripheral Blood Stem Cell Transpla
- Page 717 and 718:
Bronchoscopic Examination and Bronc
- Page 719 and 720:
Bronchoscopy in Marrow Transplantat
- Page 721 and 722:
Effect of Interleukin 2 on T Lympho
- Page 723 and 724:
c c 4) "5 Q. Ss •o 3 35 (A U «5
- Page 725 and 726:
T Lymphocyte CFU After ABMT 701 Six
- Page 727:
T Lymphocyte CFCJ After ABMT 703 no
- Page 730 and 731:
706 Panel Discussion: Session IX se
- Page 733 and 734:
Expression of Human Adenosine Deami
- Page 735 and 736:
Human ADA in Monkeys 711 to the SAX
- Page 737 and 738:
Human ADA in Monkeys 713 4 were nev
- Page 739 and 740:
Human ADA in Monkeys 715 tuted marr
- Page 741 and 742:
Electric Field-Mediated DNA Transfe
- Page 743 and 744:
Electric Field-Mediated DNA Transfe
- Page 745:
Electric Field-Mediated DNA Transfe
- Page 748 and 749:
724 Aberrant Gene Expression in AML
- Page 750 and 751:
726 Aberrant Gene Expression in AML
- Page 752 and 753:
728 Aberrant Gene Expression in AML
- Page 755 and 756:
Clonal Detection of Remission by Re
- Page 757 and 758:
Clonal Detection of Remission 733 c
- Page 759 and 760:
Clonal Detection of Remission 3 735
- Page 761:
XI. Summary
- Page 764 and 765:
740 Summary administration of the a
- Page 766 and 767:
742 Summary particularly apparent i
- Page 768 and 769:
744 Summary limited occurrence of t
- Page 771 and 772:
Concluding Remarks Karel A. Dicke I
- Page 773 and 774:
Contributors and Participants Zora
- Page 775 and 776:
Contributors and Participants 751 M
- Page 777 and 778:
Contributors and Participants 753 A
- Page 779 and 780:
Contributors and Participants 755 R
- Page 781 and 782:
Contributors and Participants 757 M
- Page 783 and 784:
Contributors and Participants Leona
- Page 785 and 786:
Contributors and Participants 761 L
- Page 787 and 788:
Contributors and Participants 763 B
- Page 789 and 790:
Contributors and Participants 765 J
- Page 791 and 792:
Contributors and Participants 767 L
- Page 793 and 794:
Contributors and Participants 769 B
- Page 795 and 796:
Contributors and Participants 771 G
- Page 797 and 798:
Contributors and Participants 773 A
- Page 799 and 800:
Contributors and Participants 775 L