Autologous Bone Marrow Transplantation - Blog Science Connections

98 Ex Vivo Marrow Purging
reflect the leukemic cells that contaminate patients' bone marrow. In the future
it would be desirable to use the patient's leukemic cells to appraise the
efficiency of such combined treatment, especially inasmuch as promising
results are emerging for growing leukemic lymphoid cells (13,14).
Development of immunopharmacological strategies for ex vivo treatment
of marrow may lead to possible eradication of the residual disease in high-risk
ALL. This first case report supports the view that this approach is feasible. To
further explore its merits, we have undertaken a pilot study in our institution.
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