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Here - Surrey and Borders Partnership NHS Foundation Trust

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Research <strong>and</strong> Audit<br />

rate of false negatives is consistently low<br />

(Twiss J et al, 2008). It is therefore<br />

recommended that all patients screening<br />

positive for BPD on the MDQ (using a<br />

cut off of 9 positive responses as a<br />

positive test) should be referred for<br />

diagnostic assessment by a professional<br />

mental health worker. Additionally a<br />

large study in a USA health centre with 1<br />

million adult members identified that by<br />

administering one off screening for BPD<br />

to patients presenting with depressive<br />

symptoms, <strong>and</strong> following up positive<br />

screening results with a referral to a<br />

psychiatrist, reduced 5 year health care<br />

costs for that health centre by an<br />

estimated $1.94 million. This reduction<br />

was mostly due the difference in<br />

treatment costs between recognized<br />

versus unrecognized BPD sufferers<br />

(Menzin J et al, 2009).<br />

The importance of screening for<br />

hypomania/mania is that BPD sufferers<br />

are often misdiagnosed as suffering from<br />

unipolar depression, frequently leading<br />

to incorrect treatment. A single episode<br />

of mania constitutes a diagnosis of BPD,<br />

whilst an episode of hypomania should<br />

increase vigilance in looking out for<br />

future episodes of depression.<br />

Aims <strong>and</strong> Objectives of the<br />

Audit<br />

The purpose of the audit was to assess<br />

whether patients presenting to primary<br />

care practices within our catchment area<br />

were being screened for BPD.<br />

Additionally we wanted to establish how<br />

effective our service was at correctly<br />

identifying both true BPD sufferers, <strong>and</strong><br />

those suffering from other mental health<br />

conditions. We intend to examine this<br />

data <strong>and</strong> consider whether further<br />

awareness <strong>and</strong> screening is required.<br />

To summarize, our study aimed to<br />

answer 3 questions: Within the context<br />

of our service-<br />

1. Do primary care physicians <strong>and</strong><br />

Mental Health Nurse Practitioners<br />

(MHNPs), specialist psychiatric nurses<br />

working in both primary <strong>and</strong><br />

secondary care, screen for BPD?<br />

2. Does screening for BPD increase the<br />

likelihood of identifying this<br />

condition?<br />

3. Is there a good correlation between<br />

the diagnosis proposed by GPs <strong>and</strong><br />

MHNPs <strong>and</strong> the final diagnosis made<br />

by the psychiatrist?<br />

St<strong>and</strong>ard<br />

Currently no gold st<strong>and</strong>ard or NICE<br />

guidelines exist regarding screening for<br />

BPD in primary care; therefore we did<br />

not stipulate the use of a specific<br />

screening tool for our study. There are<br />

also no globally agreed cut-off points for<br />

what constitutes an acceptable<br />

screening test, although most<br />

researchers would agree that any good<br />

screening measure should have both a<br />

low false positive rate <strong>and</strong> a low false<br />

negative rate. The actual values that a<br />

researcher may deem acceptable are<br />

related to several variables, such as<br />

prevalence of condition, cost of<br />

screening <strong>and</strong> burden associated with<br />

missing the condition vs. burden<br />

associated with over diagnosing the<br />

condition (Simon S, 2007). For the<br />

purposes of our study, we set 80%<br />

sensitivity <strong>and</strong> 80% specificity as the<br />

st<strong>and</strong>ard, based upon levels set in other<br />

published research (Twiss J et al, 2008).<br />

Although these are arbitrary cut-off<br />

values, they are in line with generally<br />

accepted st<strong>and</strong>ards for psychiatric<br />

screening tests.<br />

Although we did not require the use of a<br />

specific screening tool for this study, we<br />

previously mentioned that a brief <strong>and</strong><br />

acceptable screening tool is available,<br />

<strong>and</strong> we may consider using this tool<br />

routinely in the future.<br />

10 <strong>Surrey</strong> <strong>and</strong> <strong>Borders</strong> Online Journal www.sabp.nhs.uk/journal

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