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Injuries of nerves and their consequences - Reflex Sympathetic ...

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NEURO-PHYSIOLOGY. 51<br />

patliologist.<br />

As concerns the individual nerve, the facts<br />

are as follows:<br />

"When a nerve is placed in a dense solution <strong>of</strong> certain<br />

salines it is at first excited, <strong>and</strong> then finally loses its functional<br />

powers, which may again be restored by placing it<br />

in water.<br />

If a nerve be slowly <strong>and</strong> carefully desiccated to a certain<br />

it is ex-<br />

degree by warmth, or mere exposure to the air,<br />

cited for a time so as to convulse its connected muscles,<br />

<strong>and</strong> at last ceases to be irritable until moistened anew.<br />

On the other h<strong>and</strong>, when we place <strong>nerves</strong> in distilled<br />

water, they lose <strong>their</strong> capacity to be excited, but regain<br />

it again when the balance is restored, by soaking them in<br />

weak solutions <strong>of</strong> phosphate <strong>of</strong> soda. Indeed, so delicate<br />

is the status <strong>of</strong> the nerve, so easily is it disturbed, that<br />

mere separation from the centres, or exposure short <strong>of</strong><br />

perceptible desiccation, modifies the excitability <strong>of</strong> the<br />

fibres.<br />

We have thus learned that every modification in the<br />

amount <strong>of</strong> water, either towards desiccation or towards<br />

excess, tends to alter, <strong>and</strong> finally to abolish, the neurility<br />

<strong>of</strong> a nerve, while a restoration <strong>of</strong> the aqueous suppl}^ or<br />

a loss <strong>of</strong> fluid by the water-soaked nerve, will, in either<br />

case, suffice to restore its function.<br />

As I have previously said, these are purely physiological<br />

experiments, <strong>and</strong> nothing akin to them is seen in man, except<br />

by rare opportunity in wounds exposed to improper<br />

dressings, or on the surface <strong>of</strong> ulcers. At first thought<br />

it<br />

might seem as if conditions <strong>of</strong> anoemia or hydrsemia<br />

<strong>of</strong>lfered some analogy to that one <strong>of</strong> the conditions just<br />

now described as an oversupply <strong>of</strong> fluid to the nerve ;<br />

but in hydrsBmia, the pathological approach to this state,<br />

there are probably more complex changes in the nutritive<br />

supplies besides those arising from a too fluid blood.<br />

The opposite condition is best represented among diseased

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