Complex Regional Pain Syndrome - Reflex Sympathetic Dystrophy ...

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Why Me? • Why, after identical lesions, does one develop CRPS while another has no pain problem at all? » • Genetic predisposition – Women with certain HLA profiles seem predisposed to CRPS – Familial frequency reported by Griepp and Thomas – Genetic traits of autonomy in rats • Disuse • Psychological factors – No good evidence
Summary • CRPS has an extremely complex pathophysiology involving sensory, motor and autonomic abnormalities • It is unknown as to how the autonomic abnormalities and inflammatory processes affect the pain and sensory/motor abnormalities • It is unknown if and how the syndrome can be prevented
Page 1 and 2: Complex Regional Pain Syndrome: Pat
Page 5: HEAT HYPERALGESIA IN CRPS • Early
Page 9 and 10: COLD ALLODYNIA IN CRPS • Late phe
Page 11 and 12: Pathophysiologic Mechanisms of CPRS
Page 13 and 14: Sensory Abnormalities in CRPS What
Page 15 and 16: Neuropathic Pain Sympathetically In
Page 17 and 18: Complex Regional Pain Syndrome and
Page 19 and 20: Sympathetic Nervous System and Pain
Page 21 and 22: Nerve Injury •Cross talk between
Page 23 and 24: Autonomic Dysfunction • Hyperhydr
Page 25 and 26: Neurogenic Inflammation • Extensi
Page 27 and 28: Motor Abnormalities • About 50% o
Page 29 and 30: Other Possible Mechanisms • Persi
Page 31 and 32: Nerve Injury •Cross talk between
Page 33 and 34: Nerve Injury Dorsal Horn Sprouting
Page 35: Nerve Injury Activation of non neur

Complex Regional Pain Syndrome - Reflex Sympathetic Dystrophy ...

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