Complex Regional Pain Syndrome - Reflex Sympathetic Dystrophy ...

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Neurogenic Inflammation What we know • Neurogenic processes are involved in the pathogenesis of early CRPS What we don’t know • The mechanisms that initiate and maintain the inflammatory reaction • The role of the sympathetic nervous system in the early inflammatory state
Motor Abnormalities • About 50% of CRPS patients develop – Decreased range of motion – Physiological tremor – Reduction in active motor force • About 10% of CRPS patients develop dystonia in the affected extremity Schwartzman and Kerrigan, 1990; Deuschl et al, 1991; Marsden et al, 1984; Bhatia et al, 1993
Page 1 and 2: Complex Regional Pain Syndrome: Pat
Page 5: HEAT HYPERALGESIA IN CRPS • Early
Page 9 and 10: COLD ALLODYNIA IN CRPS • Late phe
Page 11 and 12: Pathophysiologic Mechanisms of CPRS
Page 13 and 14: Sensory Abnormalities in CRPS What
Page 15 and 16: Neuropathic Pain Sympathetically In
Page 17 and 18: Complex Regional Pain Syndrome and
Page 19 and 20: Sympathetic Nervous System and Pain
Page 21 and 22: Nerve Injury •Cross talk between
Page 23 and 24: Autonomic Dysfunction • Hyperhydr
Page 25: Neurogenic Inflammation • Extensi
Page 29 and 30: Other Possible Mechanisms • Persi
Page 31 and 32: Nerve Injury •Cross talk between
Page 33 and 34: Nerve Injury Dorsal Horn Sprouting
Page 35 and 36: Nerve Injury Activation of non neur
Page 37 and 38: Summary • CRPS has an extremely c

Complex Regional Pain Syndrome - Reflex Sympathetic Dystrophy ...

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