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Complex Regional Pain Syndrome - Reflex Sympathetic Dystrophy ...

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Autonomic Dysfunction<br />

• About 85% of CRPS report pain relief after<br />

sympathetic interruption; however, the pain relief<br />

is temporary in the majority of patients<br />

• Catecholamines can activate peripheral<br />

nociceptors after thermal or chemical sensitization<br />

in the absence of nerve injury<br />

• After nerve injury, surviving cutaneous afferents<br />

develop noradrenergic sensitivity

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