A sustainable business model based on innovation and ... - Roche
A sustainable business model based on innovation and ... - Roche
A sustainable business model based on innovation and ... - Roche
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Exciting mid / early-stage opportunities in <strong>on</strong>cology<br />
3rd generati<strong>on</strong> anti-CD20- potential for improvement over<br />
MabThera <str<strong>on</strong>g>based</str<strong>on</strong>g> <strong>on</strong> Glycart technology<br />
Improved product features<br />
Increased direct cell death<br />
Increased ADCC<br />
Lower CDC<br />
Phase I in NHL<br />
Extended patent life for many<br />
other m<strong>on</strong>ocl<strong>on</strong>cal antibodies?<br />
MabThera<br />
Herceptin<br />
Pertuzumab.<br />
GA101: Phase II <strong>on</strong>going<br />
Phase I data presented at ASH 2009<br />
ADCC= (antibody dependent cell-mediated cytotoxicity); CDC= (complement dependent cytotoxicity)<br />
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