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A sustainable business model based on innovation and ... - Roche

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Resp<strong>on</strong>sible management of R&D spend<br />

Higher attriti<strong>on</strong> in early stage - higher success in late stage<br />

100<br />

90<br />

100<br />

80<br />

60<br />

40<br />

Success Rate (%)<br />

80<br />

70<br />

Preclinical, Phase I <strong>and</strong> II Phase III <strong>and</strong> Registrati<strong>on</strong><br />

Industry Median<br />

<strong>Roche</strong><br />

20<br />

Industry Median<br />

<strong>Roche</strong><br />

Attriti<strong>on</strong> Rate (%)<br />

60<br />

0<br />

'95-'99<br />

'96-'00<br />

'97-'01<br />

'98-'02<br />

'99-'03<br />

'00-'04<br />

'01-'05<br />

'02-'06<br />

'95-'99<br />

'96-'00<br />

'97-'01<br />

'98-'02<br />

'99-'03<br />

'00-'04<br />

'01-'05<br />

'02-'06<br />

Source: R&D General Metrics Study, KMR GROUP, INC

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