Microsoft PowerPoint - Roche IR Event EULAR Final.ppt

Multiple sclerosis
An emerging therapeutic area for Roche
• MS is a common neurological disease affecting more
than 1 million people worldwide
• Multifocal inflammatory disease that damages the myelin
of CNS and causes neurological impairment and,
frequently, severe disability
• Commonest cause of neurological disability in young and
middle-aged adults
• Prevalence of MS varies by geographical areas
– high prevalence: Europe, Northern US, Canada, AUS
– low prevalence: Japan and Africa
• More common in women (2:1), Caucasians
MRI allows clinicians to detect and
follow pathological progression of
disease & response to treatment
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