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Microsoft PowerPoint - Roche IR Event EULAR Final.ppt

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Efficacy with repeat treatment<br />

In DMARD and TNF inadequate responders<br />

1 or more courses<br />

of RTX<br />

2 or more courses<br />

of RTX<br />

3 or more courses > 3 courses of RTX No. patients with > 24<br />

of RTX<br />

(1 g x 2) + MTX<br />

weeks<br />

with an <strong>IR</strong> to TNF inhibitors * FU post 3 rd course<br />

210<br />

97<br />

1053<br />

68<br />

400<br />

94<br />

57<br />

Patients receiving > 3 courses of<br />

rituximab (1 g x 2) + MTX with an <strong>IR</strong><br />

to DMARDs *<br />

*Patients who had initially received rituximab (0.5 g x 2) + MTX or rituximab monotherapy were excluded from the efficacy analyses<br />

41

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