Microsoft PowerPoint - Roche IR Event EULAR Final.ppt
Microsoft PowerPoint - Roche IR Event EULAR Final.ppt
Microsoft PowerPoint - Roche IR Event EULAR Final.ppt
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Adverse events<br />
Consistent with those seen in previous studies<br />
• Infusions generally well tolerated<br />
• Low incidence of adverse GI events (1 peridiverticular abscess, 1 gastroenteritis)<br />
• Transient ALT elevation – no evidence of clinical hepatitis or hepatic failure<br />
• Lipid levels initially increased and subsequently stabilised at the upper level of<br />
normal - no relevant change in atherogenic risk index<br />
• Slight increase in infections (including serious infections) over placebo<br />
– No occurrence of TB<br />
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