to view our brochure - Research Institute for Fragrance Materials

The RIFM Database: The most comprehensive database
of fragrance and flavor materials in the world.
RIFM SCIENCE
RIFM’s extensive scientific program provides the
most complete evaluations on the safe use of
fragrance raw materials and includes Human
Health, Respiratory, and Environmental endpoints.
All data collected by RIFM for their evaluations are
housed in the RIFM Database.
The Quantitative Risk Assessment (QRA)
determines safe use levels of fragrance ingredients
in a variety of consumer product types to prevent
dermal sensitization.
The EDEN Project – the European Dermato-
Epidemiology Network (EDEN) under the guidance
of the Expert Panel designed an original study to
determine the prevalence of contact allergy in the
general population.
Aggregate Exposure Model – assesses
aggregated consumer exposure to fragrance
ingredients from various products in use daily by
the typical consumer.
RIFM is developing alternative methods for testing
fragrance materials for Human Health, Respiratory
and Environmental endpoints. A number of models
are available to RIFM Database subscribers.
RIFM Respiratory Models
▲ 2-Box Indoor Air Dispersion Model assesses
inhalation exposure.
▲ Computational Fluid Dynamics (CFD) and
Multiple Path Particle Deposition (MPPD)
are in silico predictive dosimetry profilers that
locate and quantify materials deposited in the
respiratory tract to assess potential biological
effects following inhalation exposure.
AN EXPERT PANEL REVIEWS
RIFM SCIENCE
All of RIFM's scientific findings are reviewed by an
Expert Panel – internationally renowned
dermatologists, pathologists, toxicologists,
respiratory, reproduction and environmental
scientists. And, additional expertise is provided by
adjunct groups when needed. The Expert Panel
evaluates the safety of fragrance ingredients under
conditions of intended use and their independent
evaluations are published in peer-reviewed
scientific journals. The decisions of the Expert Panel
regarding restrictions of fragrance ingredient use
are also published as an IFRA Standard, available
to the public at www.ifraorg.org.
RIFM’s well-documented conclusions from
comprehensive analysis translate to enhanced
product management – resulting in safer
and more life-enriching products for the
consumer.
The Member Advantage
THE RIFM DATABASE
Through extensive research, testing and constant
monitoring of pertinent scientific literature, RIFM maintains
the most comprehensive Database, worldwide, of
toxicological, eco-toxicological data and physical-chemical
properties associated with known fragrance and flavor
materials. The RIFM Database covers more than 5,700
substances, categorized by CAS numbers, and contains
related synonyms, regulatory, inventory, occupational and
industry labeling information.
Access to the most comprehensive database of
fragrance and flavor material available 24 hours a
day, 7 days a week.
Membership in RIFM is open to all companies
that manufacture, sell, distribute or engage in business
related to the fragrance industry for at least one year.
View RIFM’s Global Member List at
www.rifm.org
Membership in RIFM expands your network to include
fragrance industry leaders, RIFM, IFRA and fragrance
industry scientists and other experts in the scientific and
academic communities.
RIFM Members
▲ Receive discounted subscriptions to the RIFM Database
▲ Receive free or discounted Letters of Access (LoAs) to
RIFM funded studies used for material registration
▲ Receive free or discounted RIFM publications
▲ Receive free or discounted registration for RIFM
educational offerings—in-person or webinar
▲ Rely on the expertise of RIFM staff scientists to address
technical needs and questions
▲ May request materials research and review by the
independent Expert Panel
Open Communication based on real science. The world's leading authorities on
Fragrance Safety protect the consumer by setting the highest standards for fragrance
use in personal and home care products.