Neuroimaging Christopher Bever, MD, MBA (MODERATOR) Use of ...

Evidence-Based Studies to Define Treatment
Failure
Classification Parameters & Outcome Measure
• Rudick et al (2004)
• Rio et al (2008)
• Durelli et al (2008)
• Kinkel et al (2008)
Gd/New T2 /Relapse
Active Lesions (N,E,Gd+)
Active MRI (and Nab)
Gd+ and T2
Outcome Measure – atrophy, disability, clinical event