Population PKPD Mode.. - Pharsight Corporation
Population PKPD Mode.. - Pharsight Corporation
Population PKPD Mode.. - Pharsight Corporation
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Example of predictive check<br />
Drug ROP Men 1 Men Drug ROP 1 Women Drug BUP 2<br />
Concentrations and predictions in "mg/L"<br />
2.0<br />
1.5<br />
1.0<br />
0.5<br />
90 % PI<br />
Cobs<br />
PRED<br />
2.0<br />
1.5<br />
1.0<br />
0.5<br />
90 % PI<br />
Cobs<br />
PRED<br />
2.0<br />
1.5<br />
1.0<br />
0.5<br />
90 % PI<br />
Cobs<br />
PRED<br />
0.0<br />
Vd/F=366 L<br />
0.0<br />
Vd/F=208 L<br />
0.0<br />
0 5 10 15 20 25 30<br />
0 5 10 15 20 25 30<br />
0 5 10 15 20 25 30<br />
TIME "Hr"<br />
TIME "Hr"<br />
TIME "Hr"<br />
slide 49<br />
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