Population PKPD Mode.. - Pharsight Corporation
Population PKPD Mode.. - Pharsight Corporation
Population PKPD Mode.. - Pharsight Corporation
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Examples of Graphs to Aid Covariate <strong>Mode</strong>l Building<br />
Explore collinearity between covariates<br />
19<br />
17<br />
15<br />
13<br />
11<br />
70<br />
60<br />
50<br />
40<br />
30<br />
20<br />
0.45<br />
0.20<br />
-0.05<br />
-0.30<br />
-0.55<br />
-0.80<br />
CRCL<br />
0 50 100150200250<br />
11 13 15 17 19<br />
MTX<br />
HT<br />
150 160 170 180<br />
20 30 40 50 60 70<br />
AGE<br />
WT<br />
40 60 80 100 120<br />
-0.80 -0.55 -0.30 -0.050.20.45<br />
ETACL<br />
ETAKA<br />
-3 -2 -1 -0 1<br />
250<br />
200<br />
150<br />
100<br />
50<br />
0<br />
180<br />
170<br />
160<br />
150<br />
120<br />
100<br />
80<br />
60<br />
40<br />
1<br />
-0<br />
-1<br />
-2<br />
-3<br />
slide 39<br />
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