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Population PKPD Mode.. - Pharsight Corporation

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Examples of GOF Plots<br />

Covariance needed between Eta’s ? (Plot from run with diagonal Omega)<br />

-0.8 -0.3 0.2 0.7<br />

1<br />

ETA1<br />

-0<br />

-1<br />

-2<br />

0.7<br />

-3<br />

0.2<br />

ETA2<br />

-0.3<br />

-0.8<br />

0.75<br />

0.50<br />

ETA3<br />

0.25<br />

0.00<br />

-0.25<br />

-3 -2 -1 -0 1<br />

-0.50 -0.25 0.00 0.25 0.50 0.75<br />

-0.50<br />

slide 31<br />

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