Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
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Perspectives<br />
• Grow<strong>in</strong>g use <strong>of</strong> drug-disease-trial <strong>Model<strong>in</strong>g</strong> & <strong>Simulation</strong> will<br />
<strong>in</strong>fluence drug development decisions …<br />
Portfolio<br />
• Which <strong>in</strong>dications should we pursue?<br />
• At what level <strong>of</strong> <strong>in</strong>vestment?<br />
Program<br />
• What trials should we conduct, <strong>and</strong> when?<br />
• When should we stop development?<br />
Trial<br />
• Which endpo<strong>in</strong>ts should we study?<br />
• Which doses <strong>and</strong> what arm sizes?<br />
Slide 32<br />
© Tripos, L.P. 2011 All Rights Reserved
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