Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
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Case Study 2: Value Delivered<br />
Impact<br />
• <strong>Model<strong>in</strong>g</strong> strategy provided sponsor timely <strong>and</strong> compell<strong>in</strong>g<br />
support for positive efficacy signal <strong>of</strong> <strong>in</strong>-licens<strong>in</strong>g c<strong>and</strong>idate,<br />
help<strong>in</strong>g to secure $23 million f<strong>in</strong>anc<strong>in</strong>g round <strong>and</strong> advance<br />
compound to Phase IIb<br />
Extensions<br />
• Potential for models to be comb<strong>in</strong>ed with Phase IIb data to<br />
support downstream trial design <strong>and</strong> program strategy decisions<br />
(e.g., mak<strong>in</strong>g predictions about steady-state HbA1c)<br />
Slide 30<br />
© Tripos, L.P. 2011 All Rights Reserved
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