Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
Role of PKPD Modeling and Simulation in Influencing ... - Pharsight
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
… <strong>and</strong> Strategically<br />
Application <strong>of</strong> <strong>in</strong>tegrated drug-disease-trial models to<br />
optimize cl<strong>in</strong>ical development programs with respect to<br />
therapeutic potential, R&D productivity <strong>and</strong> commercial<br />
value.<br />
Trial Data<br />
Disease<br />
Model<br />
Drug<br />
Model<br />
Diverse<br />
Expertise<br />
Physiology<br />
Trial<br />
Model<br />
‣Biology<br />
‣Natural Progression<br />
‣Placebo<br />
‣Biomarker-Outcome<br />
‣Pharmacology<br />
‣Effectiveness<br />
‣Safety<br />
‣Early-Late<br />
‣Precl<strong>in</strong>ical-Healthy-Patient<br />
‣Patient Population<br />
‣Drop-out<br />
‣Compliance<br />
Graphic provided courtesy <strong>of</strong> Dr. Joga Gobburu, OCP/FDA.<br />
Slide 18<br />
© Tripos, L.P. 2011 All Rights Reserved
Change language