Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Mark Cushman
87. K. Iwasa, M. Kamigauchi, N. Takao, and M. Cushman, "Stereochemical Studies on the
Biosynthesis of Protoberberine, Protopine, and Benzophenanthridine Alkaloids Using
Papaveraceae Cell Cultures," J. Nat. Prod. 56, 2053 (1993).
88. A. Bacher, K. Ritsert, K. Kis, K. Schmidt-Bäse, R. Huber, R. Ladenstein, J. Scheuring, S.
Weinkauf, and M. Cushman, "Studies on the Biosynthesis of Flavins. Structure and
Mechanism of 6,7-Dimethyl-8-ribityllumazine Synthase," Flavins and Flavoproteins
1993, Walter de Gruyter and Co., Berlin, 1994, pp 53-62.
89. J. Scheuring, J. Lee, M. Cushman, H. Oschkinat, and A. Bacher, " 19 F NMR Studies on
Lumazine Protein from Photobacterium phosphoreum," Flavins and Flavoproteins 1993,
Walter de Gruyter and Co., Berlin, 1994, pp 75-78.
90. J. Scheuring, M. Cushman, H. Oschkinat, and A. Bacher, " 19 F NMR Studies on the
Mechanism of Riboflavin Synthase," Flavins and Flavoproteins 1993, Walter de Gruyter
and Co., Berlin, 1994, pp 79-82.
91. E.-S. Lee and Mark Cushman, "Synthesis of a Phosphotyrosine-containing Peptide
Fragment of the Regulatory Domain of pp60c-src," J. Org. Chem. 59, 2086 (1994).
92. J. Jurayj, R. D. Haugwitz, R. K. Varma, J. F. Barrett, and M. Cushman, "Design and
Synthesis of Ellipticinium Salts and 1,2-Dihydroellipticines with High Selectivities
against Human CNS Cancers In Vitro," J. Med. Chem. 37, 2190 (1994).
93. J. Scheuring, J. Lee, M. Cushman, H. Patel, D. A. Patrick, and A. Bacher,
"(Trifluoromethyl)lumazine Derivatives as 19 F NMR Probes for Lumazine Protein,"
Biochemistry 33, 7634 (1994).
94. H.-M. He and M. Cushman, "A Versatile Synthesis of 2-Methoxyestradiol, an
Endogenous Metabolite of Estradiol which Inhibits Tubulin Polymerization by Binding to
the Colchicine Binding Site," Bioorg. Med. Chem. Lett. 4, 1725-1728 (1994).
95. H.-M. He, R. L. Geahlen and M. Cushman, "Synthesis of a Series of Brominated 1-
Phenyl-2-pyridylethenes as Inhibitors of the Protein-tyrosine Kinase p56 lck ," Bioorg.
Med. Chem. Lett. 4, 1729 (1994).
96. M. Cushman, W. M. Golebiewski, J. B. McMahon, R. W. Buckheit, Jr., D. A. Clanton,
O. Weislow, R. D. Haugwitz, J. P. Bader, L. Grahm, and W. G. Rice, "Design, Synthesis,
and Biological Evaluation of Cosalane, a Novel Anti-HIV Agent which Inhibits Multiple
Features of Virus Replication," J. Med. Chem. 37, 3040 (1994).
97. K. Thakkar and M. Cushman, "A Novel Oxidative Cyclization of 2'-Hydroxychalcones to
4-Methoxyaurones by Thallium(III) Nitrate," Tetrahedron Lett. 35, 6441 (1994).
98. E. S. Lee, J. J. Jurayj, and M. Cushman, "Synthesis of [L-3-deoxymimosine(4)]-
angiotensin I as an Approach to the Preparation of Selective Protein-tyrosine Kinase
(PTK) Inhibitors," Tetrahedron 50, 9873 (1994).
99. Y.-i. Oh and M. Cushman, "Synthesis and Anti-HIV Activity of Poly(cysteic acid),"
Bioorg. Med. Chem. Lett. 4, 2245 (1994).
100. M. Cushman, H. Zhu, R. L. Geahlen, and A. J. Kraker, "Synthesis and Biochemical
Evaluation of a Series of Aminoflavones as Potential Inhibitors of Protein-Tyrosine
Kinases p56 lck , EGFr, and p60 v-src , "J. Med. Chem. 37, 3353 (1994).
101. J. Scheuring, M. Cushman, and A. Bacher, "Elimination of the 7-Trifluoromethyl Group
from 6,7-Bis(Trifluoromethyl)-8-ribityllumazines. Stereoselective Catalysis by the
Lumazine Synthase of Bacillus subtilis, " J. Org. Chem. 60, 243 (1995).
102. M. Cushman, W. M. Golebiewski, Y. Pommier, A. Mazumder, D. Reymen, E. De Clercq,
L. Grahm, and W. G. Rice, "Cosalane Analogues with Enhanced Potencies as Inhibitors
of HIV-1 Protease and Integrase," J. Med. Chem. 38, 443 (1995).
103. M. Cushman, P. Wang, D. Reymen, J. Este, M. Witvrouw, J. Neyts, and E. De Clercq,
"Anti-HIV and Anti-HCMV Activities of New Aurintricarboxylic Acid Analogues,"
Antiviral Chem. Chemother. 6, 179-186 (1995).
104. M. Cushman, H.-M. He, J. A. Katzenellenbogen, C. M. Lin, and E. Hamel, "Synthesis,
Antitubulin and Antimitotic Activity, and Cytotoxicity of Analogs of 2-
Methoxyestradiol, an Endogenous Mammalian Metabolite of Estradiol that Inhibits
Tubulin Polymerization by Binding to the Colchicine Binding Site," J. Med. Chem. 38,
2041-2049 (1995).
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