Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Mark Cushman
70. M. Cushman, D. Nagarathnam, and R. L. Geahlen, "Synthesis and Evaluation of
Hydroxylated Flavones and Related Compounds as Potential Inhibitors of the Proteintyrosine
Kinase p56 lck ," J. Nat. Prod. 54, 1345 (1991).
71. S. R. Byrn, D. V. Carlson, J. K. Chen, M. S. Cushman, M. E. Goldman, W. P. Ma, C. L.
Pidgeon; K. A. Ray, J. G. Stowell, and H. L. Weith, "Drug-oligonucleotide Conjugates",
Adv. Drug Delivery Rev. 6, 287 (1991).
72. M. Cushman and E.-S. Lee, "Preparation of an Angiotensin I Analog Containing a p-
Phosphonomethyl-L-phenylalanine Residue Via Asymmetric Synthesis of t-BOC-p-
Dimethylphosphonomethyl-L-Phenylalanine," Tetrahedron Lett. 33, 1193 (1992).
73. P. Wang, J. Kozlowski, and M. Cushman, "Isolation and Structure Elucidation of Low
Molecular Weight Components of Aurintricarboxylic Acid (ATA)," J. Org. Chem. 57,
3861 (1992).
74. M. Cushman and P. Sherman, "Inhibition of HIV-1 Integration Protein by
Aurintricarboxylic Acid (ATA) Monomers, Monomer Analogs, and Polymer Fractions,"
Biochem. Biophys Res. Commun. 185, 85 (1992).
75. M. Cushman, D. Nagarathnam, D. Gopal, H.-M. He, C. M. Lin, and E. Hamel, "Synthesis
and Evaluation of Analogues of (Z)-1-(4-Methoxyphenyl)-2-(3,4,5-
trimethoxyphenyl)ethene as Potential Cytotoxic and Antimitotic Agents," J. Med. Chem.
35, 2293-2306 (1992).
76. J.-k. Chen, D. V. Carlson, H. L. Weith, J. A. O'Brien, M. E. Goldman, and M. Cushman,
"Synthesis of an Oligonucleotide-Intercalator Conjugate in Which the Linker Chain is
Attached Via the Phenolic Hydroxyl Group of Fagaronine," Tetrahedron Lett. 33, 2275
(1992).
77. J. Neyts, R. Snoeck, P. Wutzler, M. Cushman, R Klöcking, B. Helbig, P. Wang, and E.
De Clercq, "Poly(hydroxy)carboxylates as Selective Inhibitors of Cytomegalovirus and
Herpes Simplex Virus Replication," Antiviral Chem. Chemother. 3, 215 (1992).
78. M. T. Konieczny and M. Cushman, "A Novel Synthesis of Compounds Containing a
Fused Pyrrole Ring from Cyclic Ketones and N-BOC-L-Phenylalaninal," Tetrahedron
Lett. 33, 6939-6940 (1992).
79. J. Jurayj and M. Cushman, "Approaches to the Synthesis of Endothiopeptides: Synthesis
of a Thioamide-Containing C-Terminal Bombesin Nonapeptide," Tetrahedron 48, 8601
(1992).
80. M. Cushman, P. Wang, J. G. Stowell, D. Schols, and E. De Clercq, "Structural
Investigation and Anti-HIV Activities of High Molecular Weight ATA Polymers," J.
Org. Chem. 57, 7241 (1992).
81. M. Cushman, H. H. Patel, J. Scheuring, and A. Bacher," 19 F NMR Studies on the
Mechanism of Riboflavin Synthase. Synthesis of 6-(Trifluoromethyl)-7-oxo-8-(Dribityl)lumazine
and 6-(Trifluoromethyl)-7-methyl-8-(D-ribityl)lumazine," J. Org. Chem.
57, 5630 (1992).
82. M. Cushman, H. H. Patel, J. Scheuring, and A. Bacher, " 19 F NMR Studies on the
Mechanism of Riboflavin Synthase. Synthesis of 6-Trifluoromethyl-8-(Dribityl)lumazine
and Derivatives," J. Org. Chem 58, 4033 (1993).
83. M. T. Konieczny, P. H. Toma, and M. Cushman, "Synthesis of Hydroxyethylene
Isosteres of the Transition State of the HIV Protease-Catalyzed Phe-Pro Hydrolysis:
Reaction of 2-(Boc)amino-1-(2'-oxocyclopentyl)-3-phenylpropanols with Diethyl
Phosphorocyanidate and Lithium Cyanide Followed by Samarium Iodide," J. Org. Chem.
58, 4619 (1993).
84. M. Cushman, H.-M. He, C. M. Lin, and E. Hamel, "Synthesis and Evaluation of a Series
of Benzylaniline Hydrochlorides as Potential Cytotoxic and Antimitotic Agents Acting
by Inhibition of Tubulin Polymerization," J. Med. Chem. 36, 2817-2821 (1993).
85. K. Thakkar, R. L. Geahlen, and M. Cushman, "Synthesis and Protein-Tyrosine Kinase
Inhibitory Activity of Polyhydroxylated Stilbene Analogs of Piceatannol," J. Med. Chem.
36, 2950 (1993).
86. W. M. Golebiewski, J. P. Bader, and M. Cushman, "Design and Synthesis of Cosalane, a
Novel anti-HIV Agent," Bioorg. Med. Chem. Lett. 3, 1739 (1993).
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