Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

4
Mark Cushman
Epicorynoline and the B-Secoprotoberberine Alkaloid Corydalic Acid Methyl Ester",
Tetrahedron Lett., 27, 2103 (1986).
37. J. Ulrichová, J. Lenfeld, M. Cushman, P. Mohan, and V. Simánek, "Comparison of
Biological Activity of some Benzo[c]phenanthridine Alkaloids and their Structural
Analogs", Acta Univ. Palacki Olomuc. (Olomouc), Fac. Med., 113, 401 (1986).
38. M. Cushman, W.C. Wong, and A. Bacher, "Synthesis of Bis(trifluoromethyl) Pyrazine-
Containing Nitrogen Heterocycles from Hexafluorobiacetyl and ortho-Diamines.
Stabilization of the Covalent Dihydrates of Pteridines and Pyrido[3,4-b]pyrazines by
Trifluoromethyl Groups", J. Chem. Soc. Perkin Trans. 1, 1043 (1986).
39. M. Cushman, W.C. Wong, and A. Bacher, "Synthesis of 6,7-Bis(trifluoromethyl)-8-
substituted Pteridine (Lumazine) Hydrates from 4,5-Diaminouracil Hydrochlorides and
Perfluorobutane-2,3-dione. Stabilization of the Transmolecular Hydrates of 8-Substituted
Pteridinediones by Trifluoromethyl Groups", J. Chem. Soc. Perkin Trans.1, 105l (1986).
40. N. Kubová, E. Smékal, V. Kleinwächter, and M. Cushman, "Binding Properties of
Nitidine and Its Indenoisoquinoline Analogue with DNA", Studia Biophys., 114, 25l
(1986).
41. E. Smëkal, N. Kubová, V. Kleinwächter, and M. Cushman, "DNA-Binding Studies-
Selected Benzophenanthridine Alkaloids as Binding Probes", Studia Biophys., 114, 257
(1986).
42. M. Cushman and E.J. Madaj, "A Study and Mechanistic Interpretation of the Electronic
and Steric Effects that Determine the Stereochemical Outcome of the Reaction of Schiff
Bases with Homophthalic Anhydride and 3-Phenylsuccinic Anhydride," J. Org. Chem.,
52, 907 (1987).
43. M. Cushman and J.-k. Chen, "Utilization of the l-Ferrocenyl-2-methylpropyl Substituent
and a Chiral Auxiliary in the Asymmetric Synthesis of the Benzophenanthridine
Alkaloids (+)- and (-)-Corynoline," J. Org. Chem., 52, 1517 (1987).
44. M. Cushman, H. Patel, and A. McKenzie, "Synthesis of Trifluoromethylated Pyrazine-
Containing Nitrogen Heterocycles From Trifluoropyruvaldehyde and Ortho-Diamines:
Scope and Regiochemistry," J. Org. Chem., 53, 5088 (1988).
45. K. Iwasa, M. Kamigauchi, N. Takao, M. Cushman, W.C. Wong, and J.-K. Chen,
"Formation of Benzo[c]phenanthridines by Oxidative C-N Bond Fission Followed by
Intramolecular Recyclization in Cell Cultures of Corydalis incisa," Tetrahedron Lett., 29,
6457 (1988).
46. K. Iwasa, M. Kamigauchi, N. Takao, M. Cushman, J.-K. Chen, W.C. Wong, and A.
McKenzie, "Synthesis and Evaluation of Hypothetical Intermediates in the Biosynthetic
Conversion of Protoberberine to Benzo[c]phenanthridine Alkaloids. Evidence for
Oxidative C-N Bond Cleavage Followed by Intramolecular Recyclization in Cell
Cultures of Corydalis incisa," J. Amer. Chem. Soc., 111, 7925 (1989).
47. M. Cushman, D.A. Patrick, P.H. Toma, and S.R. Byrn, "A Novel Ring System Arising
From Intramolecular Oxidative Cyclization of 8-(4-Pentyl)dihydroberberine,"
Tetrahedron Lett., 30, 7161 (1989).
48. M. Cushman and S. Kanamathareddy, "Synthesis of the Covalent Hydrate of the
Incorrectly Assumed Structure of Aurintricarboxylic Acid," Tetrahedron, 46, 1491
(1990).
49. M. Cushman, J. Jurayj, and J. D. Moyer, "Synthesis, Biological Testing and
Stereochemical Assignment of an End Group Modified Retro-Inverso Bombesin C-
Terminal Nonapeptide," J. Org. Chem., 55, 3186 (1990).
50. M. Cushman and J. Jurayj, "A Synthesis of 2-Alkyl and 2-Benzyl Substituted
Acrylonitriles from 2-Alkyl and 2-Benzylidene Cyanoacetate Esters under Mild
Conditions," Synth. Commun., 20, 1463 (1990).
51. M. Cushman, P. Chinnasamy, D. A. Patrick, A. T. McKenzie, and P. H. Toma, "A Novel
Ring Expansion Observed during the Lithium Aluminum Hydride Reduction of 13-
Nitrooxyberberine," J. Org. Chem ., 55, 5995 (1990).
52. M. Cushman, H. H. Patel, D. A. Patrick, A. Bacher, and K. Schott, "Synthesis of
Fluorinated 8-Ribityllumazines as 19 F NMR Probes and Potential Inhibitors of the Light
Riboflavin Synthase of Bacillus subtilis" in "Chemistry and Biology of Pteridines 1989,