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Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

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Mark Cushman<br />

303. J.-H. Liang, W. Lv, X.-L. Li, K. An; M. Cushman, H. Wang, and Y.-C. Xu, " Synthesis<br />

and Antibacterial Activity <strong>of</strong> 9-Oxime Ether Non-ketolides, and Novel Binding Mode <strong>of</strong><br />

Alkylides with Bacterial rRNA," Bioorg. Med. Chem. Lett. 23, 1387–1393 (2013).<br />

Intellectual Property Disclosures (since 2007):<br />

1. "Anti-trypanosomal activity <strong>of</strong> topoisomerase IB-targeting indenoisoquinolines", Mark S.<br />

Cushman, Andrew Morrell, Dongpei Sang, Rahul Bakshi, and Theresa Shapiro, June 12,<br />

2007.<br />

2. "Hydrolytically Stable Alkenyldiarylmethane Non-nucleoside Reverse Transcriptase<br />

Inhibitors," Mark S. Cushman and Matthew Cullen, March 1, 2007.<br />

3. "14-Substituted Aromathecin Topoisomerase I Inhibitors," Mark S. Cushman, Maris<br />

Cinelli, Andrew Morrell, and Yves Pommier, April 17, 2008.<br />

4. "Rib<strong>of</strong>lavin Synthase Inhibitors as Potential Antitubercular Agents," Mark S. Cushman,<br />

Yanlei Zhang, Markus Fischer, and Adelbert Bacher, April 8, 2009.<br />

5. "Discovery <strong>of</strong> a Novel Indenoisoquinoline Inducer <strong>of</strong> the Retinoid X Receptor Response<br />

Element (RXRE)," Mark S. Cushman, John M. Pezzuto, Eun-Jung Park, and Andrew<br />

Morrell, June 2, 2009.<br />

6. "Casimiroin-Based Aromatase and QR2 Inhibitors," Mark S. Cushman, John M. Pezzuto,<br />

and Arup Maiti, January 21, 2009.<br />

7. "New Antitumor Norindenoisoquinoline Topoisomerase I Inhibitors," Mark S. Cushman,<br />

Yunlong Song, and Yves Pommier, August 11, 2009.<br />

8. "Substituted Dibenzo[c,h]naphthyridinediones, 11-Chlorodibenzo[c,h]naphthyridinones<br />

and Dibenzo[c,h]naphthyridines as Topoisomerase I Inhibitors and Potential Anticancer<br />

Agents," Mark S. Cushman, Evgeny Kiselev, and Yves Pommier, June 10, 2010.<br />

9. "Indenoisoquinoline Topoisomerase I Inhibitors Substituted with Carbohydrates," Mark<br />

S. Cushman, Katherine Peterson, Maris Cinelli, Andrew Morrell, and Yves Pommier,<br />

October 22, 2010.<br />

10. " Potential Chemopreventive Agents Based on the Structure <strong>of</strong> the Lead Compound<br />

2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284," Mark S.<br />

Cushman and Martin Conda-Sheridan, November 1, 2010.<br />

11. "Preparation <strong>of</strong> Phenylthiazole Derivatives as Antiviral Agents," Abdelrahman Salah<br />

Mayhoub, Mansoora Khaliq, Richard Kuhn, and Mark S. Cushman, February 4, 2011.<br />

12. "Preparation <strong>of</strong> Azole Derivatives as Cancer Chemopreventive Agents," Abdelrahman<br />

Salah Mayhoub, John M. Pezzuto, and Mark S. Cushman, April 1, 2011.<br />

13. "Synthesis and Use <strong>of</strong> Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)-Topoisomerase I<br />

(Top1) Inhibitors", Mark S. Cushman and Nguyen Trung, March 8, 2012.<br />

14. "Dibenzo[c,h][1,5]naphthyridinediones as Topoisomerase I Inhibitors: Design, Synthesis,<br />

and Biological Evaluation," Mark S. Cushman and Evgeny Kiselev, March 21, 2012.<br />

15. "A Novel Synthesis <strong>of</strong> the Anticancer Drugs Indotecan (LMP400) and Indotecan<br />

(LMP776)," Mark S. Cushman, June 6, 2012.<br />

16. "Antimicrobial activity <strong>of</strong> novel substituted thiazoles against methicillin-resistant<br />

Staphylococcus aureus (MRSA)", Mark S. Cushman, Abdelrahman S. Mayhoub, and<br />

Seleem N. Mohamed, September 25, 2012.<br />

17. "Indenoisoquinoline Rexinoids with Chemopreventive Potential," Mark S. Cushman,<br />

Martin Conda-Sheridan, and John M. Pezzuto, January 7, 2013.<br />

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