Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Mark Cushman
291. A. Talukdar, Y. Zhao, W. Lv, A. Bacher, B. Illarionov, M. Fischer, and M. Cushman, "O-
Nucleoside, S-Nucleoside, and N-Nucleoside Probes of Lumazine Synthase and
Riboflavin Synthase," J. Org. Chem. 77, 6239-6261 (2012).
292. L. Chen, M. Conda-Sheridan, P. V. N. Reddy, A. Morrell, E.-J. Park, T. P. Kondratyuk,
J. M. Pezzuto, R. B. van Breemen, and M. Cushman, "Identification, Synthesis, and
Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-
c]isoquinoline-5,11-dione (AM6-36), a Promising Rexinoid Lead Compound for the
Development of Cancer Chemotherapeutic and Chemopreventive Agents," J. Med. Chem.
55, 5965-5981 (2012).
293. D. Sun, J. G. Hurdle, R. E. Lee, R. E. Lee, M. Cushman, and J. M. Pezzuto, "Evaluation
of Flavonoid and Resveratrol Chemical Libraries Reveals Abyssinone II as a Promising
Antibacterial Lead," ChemMedChem 7, 1541-1545 (2012).
294. R. Balana-Fouce, C. Prada, J. Requena, M. Cushman, Y. Pommier, R. Álvarez-Velilla, J.
Escudero-Martínez, E. Calvo-Álvarez, Y. Pérez-Pertejo, and R. Reguera "Indotecan
(LMP400) and AM13-55: Two Novel Indenoisoquinolines Show Potential for Treating
Visceral Leishmaniasis", Antimicrob. Agents Chemother. 56, 5264-5270 (2012).
295. A. S. Mayhoub, L. Marler, T. P. Kondratyuk, E.-J. Park, J. M. Pezzuto, and M.
Cushman § , "Optimization of Thiazole Analogues of Resveratrol for Induction of
NAD(P)H:quinone Reductase 1 (QR1)," Bioorg. Med. Chem. 20, 7030-7039 (2012).
296. G. Mancini, I. D'Annessa, A. Coletta, G. Chillemi, Y. Pommier, M. Cushman, and A.
Desideri, "Binding of an Indenoisoquinoline to the Topoisomerase-DNA Complex
Induces Reduction of Linker Mobility and Strengthening of Protein-DNA Interaction,"
PloS ONE 7(12): e51354. doi:10.1371/journal.pone.0051354
(http://dx.plos.org/10.1371/journal.pone.0051354).
297. M. A. Cinelli, P. V. N. Reddy, P.-C. Lv, J.-H. Liang, L. Chen, K. Agama, Y. Pommier, R.
B. van Breemen, and M. Cushman, "Identification, Synthesis, and Biological Evaluation
of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and
Indimitecan (LMP 776) and Investigation of Isomerically Hydroxylated
Indenoisoquinoline Analogues as Topoisomerase I Poisons," J. Med. Chem. 55, 10844-
10862 (2012).
298. J.-H. Liang, K. An, W. Lv, M. Cushman, H. Wang, and Y.-C. Xu, "Synthesis,
Antibacterial Activity and Docking of 14-Membered 9-O-(3-Arylalkyl)oxime 11,12-
Cyclic Carbonate Ketolides," Eur. J. Med. Chem. 59, 54-63 (2013).
299. J.-H. Liang, W. Lv, X.-L. Li, K. An, M. Cushman, H. Wang, and Y.-C. Xu, "Synthesis
and Antibacterial Activity of 9-Oxime Ether Non-ketolides, and Novel Binding Mode of
Alkylides," Bioorg. Med. Chem. Lett. 23, 1387-1393 (2013).
300. M. Conda-Sheridan, P. V. Narasimha Reddy, A. Morrell, B. T. Cobb, C. Marchand, K.
Agama, A. Chergui, A. Renaud, A. G. Stephen, L. K. Bindu, Y. Pommier, and M.
Cushman, "Synthesis and Biological Evaluation of Indenoisoquinolines That Inhibit Both
Tyrosyl-DNA Phosphodiesterase I (Tdp1) and Topoisomerase I (Top1)," J. Med. Chem.
56, 182-200 (2013).
301. D. Sun, J. G. Hurdle, R. Lee, R. Lee, M. Cushman, and J. M. Pezzuto, "Evaluation of
Flavanoid and Resveratrol Chemical Libraries Reveals Abyssinone II as a Promising
Antibacterial Lead," ChemMedChem 7, 1541-1545 (2012).
302. M. Conda-Sheridan, E.-J. Park, D. E. Beck, P. V. N. Reddy, T. X. Nguyen, B. Hu, L.
Chen, J. L. White, R. B. van Breemen, J. M. Pezzuto, and M. Cushman, "Design,
Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with
Chemopreventive Potential," J. Med. Chem. 56, 2581-2605 (2013).
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