Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

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Mark Cushman
265. R.-R. Kim, B. Illarionov, M. Joshi, M. Cushman, C. Y. Lee, W. Eisenreich, M. Fischer,
and A. Bacher, "Mechanistic Insights on Riboflavin Synthase Inspired by Selective
Binding of the 6,7-Dimethyl-8-ribityllumazine Exomethylene Anion," J. Amer. Chem.
Soc. 132, 2983-2990 (2010).
266. A. Talukdar, E. Morgunova, J. Duan, W. Meining, N. Foloppe, L. Nilsson, A. Bacher, B.
Illarionov, M. Fischer, R. Ladenstein, and M. Cushman, "Virtual Screening, Selection
and Development of a Benzindolone Structural Scaffold for Inhibition of Lumazine
Synthase," Bioorg. Med. Chem. 18, 3518-3534 (2010).
267. B. Sun, J. Hoshino, K. Jermihov, L. Marler, J. M. Pezzuto, A. D. Mesecar, and M.
Cushman, "Design, Synthesis, and Biological Evaluation of Resveratrol Analogues as
Aromatase and Quinone Reductase 2 Inhibitors for Chemoprevention of Cancer," Bioorg.
Med. Chem. 18, 5352-5366 (2010).
268. A. S. Mayhoub, A. Talukdar, and M. Cushman, "An Oxidation of Benzyl Methyl Ethers
with NBS that Selectively Affords Either Aromatic Aldehydes or Aromatic Methyl
Esters," J. Org. Chem. 75, 3507-3510 (2010).
269. J. Hoshino, E.-J. Park, T. P. Kondratyuk, L. Marler, J. M. Pezzuto, R. B. van Breemen, S.
Mo, Y. Li, and M. Cushman "Selective Synthesis and Biological Evaluation of Sulfate-
Conjugated Resveratrol Metabolites," J. Med. Chem. 53, 5033-5043 (2010).
270. P. V. N. Reddy, B. Banerjee, and M. Cushman "Efficient Total Synthesis of
Ammosamide B," Org. Lett. 12, 3112-3114 (2010).
271. M. A. Cinelli, A. E. Morrell, T. S. Dexheimer, K. Agama, S. Agrawal, Y. Pommier, and
M. Cushman, "The Structure–activity Relationships of A-Ring-substituted Aromathecin
Topoisomerase I Inhibitors Strongly Support a Camptothecin-like Binding Mode,"
Bioorg. Med. Chem. 18, 5535-5552 (2010).
272. E. Morgunova, B. Illarionov, S. Sallar, A. Popov, T. Sambaiah, A. Bacher, M. Cushman,
M. Fischer, and R. Ladenstein "Structural Study and Thermodynamic Characterization of
Inhibitor Binding to Lumazine Synthase from Bacillus anthracis," Acta Crystallogr.,
D66, 1001-1011 (2010).
273. L. Marler, M. Conda-Sheridan, M. A. Cinelli, A. E. Morrell, M. Cushman, L. Chen, K.
Huang, R. van Breemen, and J. M. Pezzuto "Cancer Chemopreventive Potential of
Aromathecins and Phenazines, Novel Natural Product Derivatives," Anticancer Res. 30,
4873-4882 (2010).
274. E. Kiselev, T. S. Dexheimer, Y. Pommier, and M. Cushman "Design, Synthesis, and
Evaluation of Dibenzo[c,h][1,6]naphthyridines as Topoisomerase I Inhibitors and
Potential Anticancer Agents," J. Med. Chem. 53, 8716-8726 (2010).
275. M. Conda-Sheridan, L. Marler, E.-J. Park, T. P. Kondratyuk, K. Jermihov, A. D. Mesicar,
J. M. Pezzuto, R. N. Asolkar, W. Fenical, and M. Cushman "Potential Chemopreventive
Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine,
Isolated from Streptomyces Species, Strain CNS284," J. Med. Chem. 53, 8688-8699
(2010).
276. E.-J. Park, T. P. Kondratyuk, A. Morrell, E. Kiselev, M. Conda-Sheridan, M. Cushman,
S. Ahn, Y. Cho, J. J. White, R. B. van Breemen, and J. M. Pezzuto, "Induction of
Retinoid X Receptor Activity and Consequent Up-regulation of p21 WAF1/CIP1 by
Indenoisoquinolines in MCF7 Cells," Cancer Prev. Res. 4, 592-607 (2011).
277. A. S. Mayhoub, M. Khaliq, R. J. Kuhn, and M. Cushman, "Design, Synthesis, and
Biological Evaluation of Thiazoles Targeting Flavivirus Envelope Proteins," J. Med.
Chem. 54, 1704-1714 (2011).
278. T. P. Kondratyuk, E.-J. Park, L. E. Marler, S. Ahn, Y. Yuan, Y. Choi, R. B. van