Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Mark Cushman
155. T. Sambaiah, P. E. Fanwick, and M. Cushman, "Regioselective 1-O-Acyl Hydrolysis of
Peracylated Glycopyranoses by Mercuric Chloride and Mercuric Oxide," Synthesis 1450-
1452 (2001).
156. G. Xu, T. L. Loftus, H. Wargo, J. A. Turpin, R W. Buckheit, Jr., and M. Cushman, "Solid
Phase Synthesis of the Alkenyldiarylmethane (ADAM) Series of Non-Nucleoside HIV-1
Reverse Transcriptase Inhibitors," J. Org. Chem. 66, 5958-5964 (2001).
157. T. Sambaiah, P. E. Fanwick, and M. Cushman, "Investigation of an Unexpected Addition
Reaction that Occurs when 2,3:4,5-Di-O-isopropylidene-D-ribose Diethyl Dithioacetal Is
Treated with Mercuric Oxide and Mercuric Chloride," J. Org. Chem. 66, 4405-4408
(2001).
158. J. Scheuring, K. Kugelbrey, S. Weinkauf, M. Cushman, A. Bacher, and M. Fischer, " 19 F
NMR Ligand Perturbation Studies on 6.7-Bis(trifluoromethyl)-8-ribityllumazine-7-
hydrates and the Lumazine Synthase Complex of Bacillus subtilis. Site-directed
Mutagenesis Changes the Mechanism and the Stereoselectivity of the Catalyzed
Haloform Reaction," J. Org. Chem. 66, 3811-3819 (2001).
159. A. Casimiro-Garcia, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Loftus, J. A.
Turpin, R. W. Buckheit, Jr., P. E. Fanwick, and M. Cushman, "Synthesis and Anti-HIV
Activity of Cosalane Analogs Incorporating Two Dichlorodisalicylmethane Fragments,"
Bioorg. Med. Chem. 9, 2827-2841 (2001).
160. S. Eberhardt, N. Ziegler, K. Kemter, G. Richter, M. Cushman, and A. Bacher, "Domain
Structure of Riboflavin Synthase," Eur. J. Biochem. 268, 4315-4323 (2001).
161. B. M. Fox, J. A. Vroman, P. E. Fanwick, and M. Cushman, "Preparation and Evaluation
of Sulfide Derivatives of the Antibiotic Brefeldin A as Potential Prodrug Candidates with
Enhanced Aqueous Solubilities," J. Med. Chem. 44, 3915-3924 (2001).
162. A. Kannan, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Hartman, J. A. Turpin, R.
W. Buckheit, Jr., and M. Cushman, "Synthesis and Anti-HIV Activity of a Bile Acid
Analog of Cosalane," Tetrahedron 57, 9385-9391 (2001).
163. G. Xu, M. Micklatcher, M. A. Silvestri, T. L. Hartman, J. Burrier, M. O. Osterling, H.
Wargo, J. A. Turpin, R. W. Buckheit, Jr., and M. Cushman, "The Biological Effects of
Structural Variation at the Meta Position of the Aromatic Ring and at the End of the
Alkenyl Chain in the Alkenyldiarylmethane Series of Non-Nucleoside Reverse
Transcriptase Inhibitors," J. Med. Chem. 44, 4092-4113 (2001).
164. M. Cushman, D. Yang, K. Kis, and A. Bacher, "Design, Synthesis, and Evaluation of 9-
D-Ribityl-1,3,7-trihydro-2,6,8-purinetrione, a Potent Inhibitor of Riboflavin Synthase and
Lumazine Synthase," J. Org. Chem. 66, 8320-8327 (2001).
165. G. Xu, T. L. Hartman, H. Wargo, J. A. Turpin, Robert W. Buckheit, Jr., and M.
Cushman, "Synthesis of Alkenyldiarylmethane (ADAM) Non-Nucleoside Reverse
Transcriptase Inhibitors with Non-Identical Aromatic Rings," Bioorg. Med. Chem. 10,
283-290 (2002).
166. M. Jayaraman, B. M. Fox, M. Hollingshead, G. Kohlhagen, Y. Pommier, and M.
Cushman, "Synthesis of New Dihydroindeno[1,2-c]isoquinoline and
Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in Vivo
Anticancer Activity in the Hollow Fiber Animal Model," J. Med. Chem. 45, 242-249
(2002).
167. K. R. Kuchimanchi, M. D. Gandhi, R. R. Sheta, T. P. Johnson, K. C. Santhosh, M.
Cushman, and A. K. Mitra, "Intestinal Absorption and Biodistribution of Cosalane and Its
Amino Acid Conjugates: Novel Anti-HIV Agents," Int. J. Pharm. 231, 197-211 (2002).
168. A. K. Mehta, D. R. Studelska, M. Fischer, A. Gieβuaf, K. Kemter, A. Bacher, M.
Cushman, and J. Schaefer, "Investigation of the Binding of Epimer A of the Covalent
Hydrate of 6,7-Bis(trifluoromethyl)-8-D-ribityllumazine to a Recombinant F22W
Bacillus subtilits Lumazine Synthase Mutant by 15 N{ 19 F} REDOR NMR," J. Org. Chem.
67, 2087-2092 (2002).
169. R. A. Hughes, T. Harris, E. Altmann, D. McAllister, R. Vlahos, A. Robertson, M.
Cushman, Z. Wang, and A. G. Stewart, "2-Methoxyestradiol and Analogues as Novel
Antiproliferative Agents: Analysis of Three-Dimensional Quantitative Structure-Activity
11