Curriculum vitae for mark cushman - Purdue College of Pharmacy ...

Mark Cushman
140. J. M. Goetz, B. Poliks, D. R. Studelska, M. Fischer, K. Kugelbrey, A. Bacher, M.
Cushman, and J. Schaefer, "Investigation of the Binding of Certain Fluorolumazines to
Lumazine Synthase by 15 N{ 19 F} REDOR NMR," J. Amer. Chem. Soc. 121, 7500-7508
(1999).
141. M. L. Micklatcher and M. Cushman, "An Improved Method for the Synthesis of 3-
Fluorosalicylic Acid with Application to the Synthesis of 3-(Trifluoromethyl)salicylic
Acid," Synthesis 1878-1880 (1999).
142. J. A. Ruell, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Stup, J. A. Turpin, R. W.
Buckheit, Jr., M. Cushman, "Synthesis and Anti-HIV Activity of Cosalane Analogues
with Substituted Benzoic Acid Rings Attached to the Pharmacophore through Methylene
and Amide Linkers," J. Org. Chem. 64, 5858-5866 (1999).
143. A. Casimiro-Garcia, M. Micklatcher, J. A. Turpin, T. L. Stup, K. Watson, R. W.
Buckheit, Jr., and M. Cushman, "Novel Modifications in the Alkenyldiarylmethane
(ADAM) Series of Non-Nucleoside Reverse Transcriptase Inhibitors," J. Med. Chem. 42,
4861-4874 (1999).
144. A. Casimiro-Garcia, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Stup, J. A.
Turpin, R. W. Buckheit, Jr., and Mark Cushman, "Synthesis and Anti-HIV Activity of
Cosalane Analogs Incorporating Nitrogen in the Linker Chain," Bioorg. Med. Chem. 8,
191-200 (2000).
145. P. Verdier-Pinard, Z. Wang, A. K. Mohanakrishnan, M. Cushman, and E. Hamel, "A
Steroid Derivative with Paclitaxel-Like Effects on Tubulin Polymerization," Molecular
Pharmacol. 57, 568-575 (2000).
146. W. Meining, S. Mörtl, S.; M. Fischer, M. Cushman, A. Bacher, R. Ladenstein, "The
Atomic Structure of Pentameric Lumazine Synthase from Saccharomyces cerevisiae at
1.85 Å Resolution Reveals the Binding Mode of a Phosphonate Intermediate Analog, " J.
Mol. Biol. 299, 181-197 (2000).
147. Z. Wang., D. Tang, A. K. Mohanakrishnan, P. E. Fanwick, P. Nampoothiri, E. Hamel,
and M. Cushman, "Synthesis of B-Ring Homologated Estradiol Analogues that Modulate
Tubulin Polymerization and Microtubule Stability," J. Med. Chem. 43, 2419-2429
(2000).
148. M. Cushman, M. Jayaraman, J. A. Vroman, A. K. Fukunaga, B. M. Fox, G. Kohlhagen,
D. Strumberg, and Y. Pommier "Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic
Non-Camptothecin Topoisomerase I Inhibitors," J. Med. Chem. 43, 3688-3698 (2000).
149. G. C. Paul, E. De Clercq, C. Pannecouque, M. Vitvrouw, T. L. Loftus, J. A. Turpin, R.
W. Buckheit, Jr., and M. Cushman, "Identification of Optimal Anion Spacing for Anti-
HIV Activity in a Series of Cosalane Tetracarboxylates," Bioorg. Med. Chem. Lett. 10,
2149-2152 (2000).
150. K. C. Santhosh, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Loftus, J. Turpin,
and R. W. Buckheit, Jr., and M. Cushman "Anti-HIV Activity of a Series of Cosalane
Amino Acid Conjugates," Bioorg. Med. Chem. Lett. 10, 2505-2508 (2000).
151. O. M. Z. Howard, H. F. Dong, J. J. Oppenheim, S. Insaf, K. C. Santhosh, G. Paul, and M.
Cushman, "Inhibition of RANTES/CCR1-Mediated Chemotaxis by Cosalane and Related
Compounds," Bioorg. Med. Chem. Lett. 11, 59-62 (2000).
152. F. Mu, S. L. Coffing, D. J. Riese II, R. L. Geahlen, P. Verdier-Pinnard, E. Hamel, J.
Johnson, and M. Cushman, "Design, Synthesis, and Biological Evaluation of a Series of
Lavendustin A Analogues That Inhibit EGFR and Syk Tyrosine Kinases, as Well as
Tubulin Polymerization," J. Med. Chem. 44, 441-452 (2001).
153. K. C. Santhosh, G. C. Paul, E. De Clercq, C. Pannecouque, M. Witvrouw, T. L. Loftus, J.
A. Turpin, R. W. Buckheit, Jr., and M. Cushman, "Correlation of Anti-HIV Activity with
Anion Spacing in a Series of Cosalane Analogs with Extended Polycarboxylate
Pharmacophores," J. Med. Chem. 44, 703-714 (2001).
154. B. Illarianov, K. Kemter, S. Eberhardt,, G. Richter, M. Cushman, and A. Bacher,
"Riboflavin Synthase of Escherichia coli. Effect of Single Amino Acid Substitutions on
Reaction Rate and Ligand Binding Properties," J. Biol. Chem. 276, 11524-11530 (2001).
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