148. J.L. White and S.L. Hem, “Characterization <strong>of</strong> Aluminium-Containing Adjuvants,” in Physico- C<strong>hem</strong>ical Procedures for the Characterization <strong>of</strong> Vaccines, Eds. F. Brown, M. Corbel and E. Griffiths, IABS Symposia Series, Developments in Biologicals, Vol. 103, Karger, Basel, 2000, pp. 217-228. 149. R. Flarend, T. Bin, D. Elmore and S.L. Hem, “A Preliminary Study <strong>of</strong> the Dermal Absorption <strong>of</strong> Aluminum from Antiperspirants Using Aluminum – 26,” Food C<strong>hem</strong>. Toxicol., 39, 163-168 (2001). 150. Y. Shi, H. HogenEsch, F.E. Regnier and S.L. Hem, “Detoxification <strong>of</strong> Endotoxin by Aluminum Hydroxide Adjuvant,” Vaccine, 19, 1747-1752 (2001). 151. M.-F. Chang, Y. Shi, S.L. Nail, H. HogenEsch, S.B. Adams, J.L. White and S.L. Hem, "Degree <strong>of</strong> Antigen Adsorption in the Vaccine or Interstitial Fluid and Its Effect on the Antibody Response in Rabbits," Vaccine, 19, 2884-2889 (2001). 152. Y. Shi, H. HogenEsch and S.L. Hem, “Change in the Degree <strong>of</strong> Adsorption <strong>of</strong> Proteins by Aluminum- Containing Adjuvants Following Exposure to Interstitial Fluid: Freshly Prepared and Aged Model Vaccines,” Vaccine, 20, 80-85 (2002). 153. N. Pongcharoenkiat, G. Narsimhan, R.T. Lyons and S.L. Hem, “The Effect <strong>of</strong> Surface Charge and Partition Coefficient on the C<strong>hem</strong>ical Stability <strong>of</strong> Solutes in O/W Emulsions,” J. Pharm Sci., 91, 559- 570 (2002). 154. C.T. Johnston, S.-L. Wang and S.L. Hem, “Measuring the Surface Area <strong>of</strong> Aluminum Hydroxide Adjuvant,” J. Pharm. Sci., 91, 1702-1706 (2002). 155. S.L. Hem, “Elimination <strong>of</strong> Aluminum Adjuvants,” Vaccine, 20, S40-S43 (2002). 156. E.A. Dandashli, Q. Zhao, S. Yitta, G. Morefield, J.L. White and S.L. Hem, “Effect <strong>of</strong> Thermal Treatment During the Preparation <strong>of</strong> Aluminum Hydroxide Adjuvant on the Protein Adsorption Capacity during Aging,” Pharm. Dev. Technol., 7, 401-406 (2002). 157. S. Iyer, H. HogenEsch and S.L. Hem, “Relationship Between the Degree <strong>of</strong> Antigen Adsorption to Aluminum Hydroxide Adjuvant in Interstitial Fluid and Antibody Production,” Vaccine, 21, 1219-1223 (2003). 158. N. Pongcharoenkiat, A. Wittayanukulluk and S.L. Hem, “Determination <strong>of</strong> Methylparaben in O/W Emulsions by Solid-Phase Extraction and High-Performance Liquid Chromatography,” J. Cosmet. Sci., 54, 47-52 (2003). 159. S. Iyer, H. HogenEsch and S.L. Hem, “Effect <strong>of</strong> the Degree <strong>of</strong> Phosphate Substitution in Aluminum Hydroxide Adjuvant on the Adsorption <strong>of</strong> Phosphorylated Proteins,” Pharm Dev. Technol., 8, 87-92 (2003). 160. C.T. Johnston, S.L. Hem, E. Guenin, J. Mattai and J. Afflito, “Potentiometric/turbidometric Titration <strong>of</strong> Antiperspirant Actives,” J. Cosmet. Soc., 54, 113–118 (2003). 161. S.-L. Wang, C.T. Johnston, D.L. Bish, J.L. White and S.L. Hem, “Water-vapor Adsorption and Surface Area Measurement <strong>of</strong> Poorly Crystalline Boehmite,” J. Colloid. Interface Sci., 260, 26–35 (2003). 162. S. Jendrek, S.F. Little, S. Hem, G. Mitra and S. Giardina, “Evaluation <strong>of</strong> the Compatibility <strong>of</strong> a Second Generation Recombinant Anthrax Vaccine with Aluminum-containing Adjuvants,” Vaccine, 21, 3011– 3018 (2003). 163. A. Bindal, G. Narsimhan, S.L. Hem and A. Kulshreshtha, “Effect <strong>of</strong> Steam Sterilization on the Rheology <strong>of</strong> Polymer Solutions,” Pharm. Dev. Technol., 8, 219-228 (2003). 16
164. D. Jiang, C.T. Johnston and S.L. Hem, “Using Rate <strong>of</strong> Acid Neutralization to Characterize Aluminum Phosphate Adjuvant,” Pharm. Dev. Technol., 8, 349-356 (2003). 165. A. Wittayanukulluk, D. Jiang, F.E. Regnier and S.L. Hem, “Effect <strong>of</strong> Microenvironment pH <strong>of</strong> Aluminum Hydroxide Adjuvant on the C<strong>hem</strong>ical Stability <strong>of</strong> Adsorbed Antigen,” Vaccine, 22, 1172- 1176 (2004). 166. S. Iyer, R.S.R. Robinett, H. HogenEsch and S.L. Hem, “Mechanism <strong>of</strong> Adsorption <strong>of</strong> Hepatitis B Surface Antigen by Aluminum Hydroxide Adjuvant,” Vaccine, 22, 1475-1479 (2004). 167. G.L. Morefield, H. HogenEsch, J.P. Robinson and S.L. Hem, “Distribution <strong>of</strong> Adsorbed Antigen in Mono-Valent and Combination Vaccines,” Vaccine, 22, 1973-1984 (2004). 168. D. Jiang, G.S. Premachandra, C. Johnston and S.L. Hem, “Structure and Adsorption Properties <strong>of</strong> Commercial Calcium Phosphate Adjuvant,” Vaccine, 23, 693-698 (2004). 169. G.L. Morefield, D. Jiang, I.Z. Romero-Mendez, R.L. Geahlen, H. HogenEsch and S.L. Hem, “Effect <strong>of</strong> Phosphorylation <strong>of</strong> Ovalbumin on Adsorption by Aluminum-containing Adjuvants and Elution Upon Exposure to Interstitial Fluid,” Vaccine, 23, 1502-1506 (2005). 170. G.L. Morefield, A. Sokolovska, D. Jiang, H. HogenEsch, J.P. Robinson and S.L. Hem, “Role <strong>of</strong> Aluminum-containing Adjuvants in Antigen Internalization by Dendritic Cells In vitro,” Vaccine, 23, 1588-1595 (2005). 171. D. Jiang, G.L. Morefield, H. HogenEsch and S. L. Hem “Relationship <strong>of</strong> Adsorption Mechanism <strong>of</strong> Antigens by Aluminum-Containing Adjuvants to In Vitro Elution in Interstitial Fluid,” Vaccine, 24, 1665-1669 (2006) 172. K. P. Yau, D. G. Schulze, C. T. Johnston and S. L. Hem, ‘Aluminum Hydroxide Adjuvant Produced Under Constant Reactant Concentration,” J. Pharm. Sci. 95, 1822-1833 (2006). 173. I.Z. Romero Mendez, Y. Shi, H. HogenEsch and S.L. Hem, “Potentiation <strong>of</strong> the Immune Response to Non-adsorbed Antigens by Aluminum-Containing Adjuvants,” Vaccine, 25, 825-833 (2007). 174. A. Bindal, G. Narsimhan, S.L. Hem and A. Kulshreshtha, “Structural Changes in Xanthan Gum Solutions During Steam Sterilization,” Pharm.Dev. Technol., in press 17