19.05.2014 Views

Fully Automated Sample Processing and HTP ... - PerkinElmer

Fully Automated Sample Processing and HTP ... - PerkinElmer

Fully Automated Sample Processing and HTP ... - PerkinElmer

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Periplasmic Targeting of Recombinant Proteins<br />

Outer membrane<br />

Periplasm<br />

Inner membrane<br />

DNA<br />

Promoter +1<br />

mRNA<br />

Cytoplasm<br />

Folding Modulators<br />

Disulfide Bond Formation<br />

Signal peptide<br />

Terminator<br />

Gene of Interest<br />

Shine-Dalgarno<br />

Oxido–reductases DsbA <strong>and</strong> DsbB<br />

Disulfide isomerases DsbD, DsbC, <strong>and</strong> DsbG<br />

Sec<br />

Recombinant<br />

Protein<br />

Signal peptidase<br />

Inactive<br />

Active Protein<br />

Extracellular space<br />

Simplified<br />

recovery<br />

Discovery ● Development ● Production

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!