Fully Automated Sample Processing and HTP ... - PerkinElmer
Fully Automated Sample Processing and HTP ... - PerkinElmer Fully Automated Sample Processing and HTP ... - PerkinElmer
Today’s Discussion Background of Pfēnex Expression Technology TM HTP expression analysis Automation of sample preparation Case Study Discovery ● Development ● Production 2
Who we are: • Located in San Diego, California • Premier technology, facility and capability in protein production and strain engineering using Pseudomonas fluorescens • Current partner programs span from discovery to clinical development stages • Pfēnex innovator programs in vaccines, reagent proteins and biosimilars/biobetters • ~32,000 square feet of space in Sorrento Valley housing capabilities in molecular biology, analytical biochemistry, fermentation, downstream processing and product development Discovery ● Development ● Production 3
- Page 1: Fully Automated Sample Processing a
- Page 5 and 6: Pfēnex HTP Strain Development >85%
- Page 7 and 8: Periplasmic Targeting of Recombinan
- Page 9 and 10: Value of Protease Deficient Hosts P
- Page 11 and 12: Process analytical: 1 st and 2 nd t
- Page 13 and 14: Expression analysis: Sample Prepara
- Page 15 and 16: Robotically Enabled Sample Preparat
- Page 17 and 18: Structure of the influenza hemagglu
- Page 19 and 20: Strains Selected for Fermentation R
- Page 21 and 22: 4-mL Fermentation PhyTip-IMAC Solub
- Page 23 and 24: Downstream Processing Robotic Batch
- Page 25 and 26: Summary Extensive genomics capabili
- Page 27: Acknowledgements: Pfenex Lauren Alc
Today’s Discussion<br />
Background of Pfēnex Expression Technology TM<br />
<strong>HTP</strong> expression analysis<br />
Automation of sample preparation<br />
Case Study<br />
Discovery ● Development ● Production<br />
2
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