Fully Automated Sample Processing and HTP ... - PerkinElmer
Fully Automated Sample Processing and HTP ... - PerkinElmer
Fully Automated Sample Processing and HTP ... - PerkinElmer
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Expression analysis: <strong>Sample</strong> Preparation Bottleneck<br />
challenge: to accurately analyze target in complex mixture of solids, protein, DNA, etc. in timely fashion<br />
samples:<br />
whole cells<br />
<strong>HTP</strong> strain selection<br />
1000s of samples<br />
Fermentation<br />
Optimization<br />
sample<br />
h<strong>and</strong>ling<br />
<strong>and</strong> cell<br />
lysis<br />
separation<br />
of soluble<br />
<strong>and</strong><br />
insoluble<br />
fractions<br />
analysis<br />
100s of samples<br />
Goal<br />
“Old” process steps<br />
semi-automated,<br />
manual labels,<br />
labor intensive<br />
centrifugation in<br />
multiple rounds;<br />
manual h<strong>and</strong>ling<br />
Improve throughput <strong>and</strong> efficiencies through automation while<br />
maintaining high-quality analytical support<br />
Discovery ● Development ● Production