Caliper GX II System Application Evaluation - PerkinElmer

Caliper GX II System Application Evaluation - PerkinElmer Caliper GX II System Application Evaluation - PerkinElmer

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Outline •Caliper Technologies GXII System Information •Assessment of Molecules Concentration and Purity Determination of Monoclonal Antibody Titer and Purity of Small Proteins (MW 10- 30KD) Analysis of Pegylated Proteins •Conclusion •Acknowledgements TYPE INFORMATION CLASSIFICATION HERE 2

Caliper Technologies GXII System An automated lab-on on-a-chip design that utilizes microfluidic capillary electrophoresis and 96/384 well plate layout in lieu of SDS- PAGE, Western Blot, and DNA/RNA gels Software generates virtual gel image based on electropherogram. Sizing Range: ~10 to 200kDa Linear Dynamic Range: 5 to 2000ng/μL TYPE INFORMATION CLASSIFICATION HERE 3

Outline<br />

•<strong>Caliper</strong> Technologies <strong>GX</strong><strong>II</strong> <strong>System</strong> Information<br />

•Assessment of Molecules<br />

Concentration and Purity Determination of<br />

Monoclonal Antibody<br />

Titer and Purity of Small Proteins (MW 10-<br />

30KD)<br />

Analysis of Pegylated Proteins<br />

•Conclusion<br />

•Acknowledgements<br />

TYPE INFORMATION CLASSIFICATION HERE<br />

2

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