Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
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von Willebrand’s Disease<br />
Laboratory Features<br />
! Normal PLT (with exceptions)<br />
! Prolonged bleed<strong>in</strong>g time<br />
! Prolonged aPTT<br />
! Decreased factor VIII activity<br />
(FVIII:C)<br />
! Decreased vWF antigen<br />
(vWF:Ag)<br />
! Abnormal ristocet<strong>in</strong> cofactor<br />
activity (vWF:RCoF)<br />
! Abnormal vWF multimeric<br />
composition<br />
! Molecular<br />
abnormalities