Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
Case Studies in Clinical Hemostasis Case Studies in ... - Pathology
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von Willebrand’s Disease<br />
Cl<strong>in</strong>ical Features<br />
! Common hereditary procoagulant disease<br />
! Frequently mild, most cases undiagnosed<br />
! Multiple cl<strong>in</strong>ical variants<br />
! Easy brusis<strong>in</strong>g very common<br />
! Mucosal bleed<strong>in</strong>g (epistaxis, GI bleed<strong>in</strong>g,<br />
menorrhagia) very common<br />
! Prolonged bleed<strong>in</strong>g after surgery or trauma<br />
a<br />
! Bleed<strong>in</strong>g caused by drugs affect<strong>in</strong>g platelet<br />
function<br />
! No history of hemarthroses or <strong>in</strong>tramuscular<br />
hematomas
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