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In conclusion, this study shows that electroporation, using electrical parameters that<br />
do not affect cell viability, induced reversible effects on actin, tubulin, but not on<br />
vimentin intracellular arrangement and disrupted VE-cadherin endothelial junctions.<br />
These changes resulted in an increase in permeability of endothelial monolayer that<br />
could potentially contribute toward transient impairment of the normal function of<br />
the microvasculature, which was observed in vivo after application of electric pulses<br />
to tumours and normal tissues.<br />
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