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probes are activated at the tumor site and the resulting fluorescence can be detected<br />
thereby revealing the position/size of the tumor in vivo. The probes are not specific<br />
to any particular tumor type, yet since there is increased expression of proteases<br />
in tumors, the resulting fluorescent products do accumulate at the tumor site. Our<br />
preliminary observations suggest that utilization of such probes will not only provide<br />
a sensitive method for cancer diagnosis, but will also provide a means to monitor<br />
therapeutic efficacy.<br />
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