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The study has shown that electrically assisted gene delivery is a successful method<br />
for plasmid DNA transfer into skeletal muscle. The optimal treatment parameters<br />
for electrically assisted gene delivery into skeletal muscle of C57Bl/6 mice in our<br />
experiments were 1HV+4LV, time interval 5 s and plasmid DNA concentration<br />
30 µg/muscle. These results are the groundwork for evaluating therapeutic protein<br />
efficiency in gene therapy and DNA vaccination.<br />
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