Structural Biology on the Grid Harvard
Structural Biology on the Grid Harvard
Structural Biology on the Grid Harvard
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Example from Harris<strong>on</strong> Lab,<br />
<strong>Harvard</strong> Medical School<br />
Our roadmap:<br />
Expand <strong>the</strong> Antibody Library to<br />
incorporate new structures<br />
Setup computati<strong>on</strong>s through a portal<br />
C<strong>on</strong>figure molecular replacement<br />
applicati<strong>on</strong>s with more advanced opti<strong>on</strong>s<br />
(e.g. rigid body refinement).<br />
Arnett et al. Crystal structure of a human CD3-epsil<strong>on</strong>/delta dimer in complex with a UCHT1 singlechain<br />
antibody fragment. Proc Natl Acad Sci USA (2004) vol. 101 (46) pp. 16268-73<br />
Ian Stokes-Rees, http://sbgrid.org
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