MOM 2006 journal for pdf.pmd - University of Michigan-Flint

idomain conductivities (σ iL
, σ iT
, σ eL
, σ eT
) as well as other tissue parameters are given in Table 1.
The conductivities in the x-y coordinate system are related to the conductivities in the fiber
coordinate system by (Roth and Langrill Beaudoin, 2003)
The active sodium channel membrane kinetics are described by the Ebihara Johnson model
(Ebihara and Johnson, 1980)
where m and h are dimensionless first order variables that vary between 0 and 1.
At the sealed surface the y-component of the current density is zero. Because the fibers
approach the surface at an angle, this boundary condition is not equivalent to the normal gradient
of the potential being zero.
Consider a rectangular strip of tissue, 5 mm x 1 mm with 800 x 161 nodes, having its upper
and lower edges sealed (Fig. 1). Initially, the tissue is at rest, -85 mV. The transmembrane
potential along the left edge is raised to +35 mV, and an action potential wave front propagates to
the right. The bidomain equations are solved using a finite difference approximation, with time
step of 0.1 μs and space step of 6.25 μm.
Meeting of Minds 2006 65