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Emerging biotechnologies: full report - Nuffield Council on Bioethics

Emerging biotechnologies: full report - Nuffield Council on Bioethics

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E m e r g i n g b i o t e c h n o l o g i e s<br />

Introducti<strong>on</strong>: a guide for the reader<br />

What is the aim of this <str<strong>on</strong>g>report</str<strong>on</strong>g>, in a nutshell?<br />

1. Biotechnologies of many forms present some of the most important sources of transformati<strong>on</strong><br />

and disrupti<strong>on</strong> in the world today. The potentialities, uncertainties and ambiguities are enormous,<br />

yet the form and directi<strong>on</strong>s taken by emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> are not a given, nor are the<br />

benefits self-evident. In practice, <strong>on</strong>ly a fracti<strong>on</strong> of the technologies that are possible can actually<br />

ever be <str<strong>on</strong>g>full</str<strong>on</strong>g>y realised. As particular developments take place, others are foreclosed; the particular<br />

technologies that are prioritised in research and development depend not <strong>on</strong>ly <strong>on</strong> the general<br />

societal benefits but also <strong>on</strong> historical chance and momentum, and the deliberate or inadvertent<br />

effects of vested interests and power. Important ethical and political issues are therefore raised,<br />

presenting significant challenges for governance. This <str<strong>on</strong>g>report</str<strong>on</strong>g> will explore these issues and<br />

challenges, and make recommendati<strong>on</strong>s to guide improved practice in policy making, in research<br />

and regulati<strong>on</strong>. The aim is to help maximise the socially beneficial and democratically<br />

accountable governance of emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>.<br />

What kind of <str<strong>on</strong>g>report</str<strong>on</strong>g> is it?<br />

2. This <str<strong>on</strong>g>report</str<strong>on</strong>g> is not focused <strong>on</strong> a particular historical development (for example, the ability to<br />

synthesise DNA) or even a particular sector (such as medicine, agriculture or industry). Nor is it<br />

addressed to a single professi<strong>on</strong>al role (research, policy making, business, etc.). Instead it<br />

addresses the shaping and selecti<strong>on</strong> of emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> (and of technological<br />

resp<strong>on</strong>ses to social challenges more generally) through the way in which decisi<strong>on</strong>s and<br />

c<strong>on</strong>diti<strong>on</strong>s in these various c<strong>on</strong>texts are related. Indeed, it is <strong>on</strong>e of the insights of the <str<strong>on</strong>g>report</str<strong>on</strong>g> that<br />

the segregati<strong>on</strong> of decisi<strong>on</strong> c<strong>on</strong>texts and the order in which they are prioritised c<strong>on</strong>stitutes a<br />

source of potential failure to maximise social value through <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>.<br />

3. Our subject is therefore not emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> as such, but how we think about emerging<br />

<str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>. The <str<strong>on</strong>g>report</str<strong>on</strong>g> is intended to stimulate thinking in a variety of different c<strong>on</strong>texts<br />

where c<strong>on</strong>diti<strong>on</strong>s that influence emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> are set. But it is a stimulus to thinking<br />

in a particular way, namely, thinking that is directed outside that immediate c<strong>on</strong>text and<br />

orientated by the shared interest in promoting the ‘public good’. Its recommendati<strong>on</strong>s are<br />

therefore largely about the processes of reflecti<strong>on</strong> and decisi<strong>on</strong> making rather than their c<strong>on</strong>tent.<br />

They are guided by a number of procedural and instituti<strong>on</strong>al virtues that underlie the ‘public<br />

ethics’ approach set out in the <str<strong>on</strong>g>report</str<strong>on</strong>g>.<br />

I N T R O D U C T I O N : A G U I D E F O R T H E R E A D E R<br />

Why does the <str<strong>on</strong>g>report</str<strong>on</strong>g> focus <strong>on</strong> ‘emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>’?<br />

4. In the <str<strong>on</strong>g>report</str<strong>on</strong>g> we treat technologies as ‘c<strong>on</strong>juncti<strong>on</strong>s of knowledges, practices, products and<br />

applicati<strong>on</strong>s’. Biotechnologies involve biological processes, systems or elements within this<br />

c<strong>on</strong>juncti<strong>on</strong>. Despite the great diversity of <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>, the c<strong>on</strong>diti<strong>on</strong>s that lead to particular<br />

c<strong>on</strong>juncti<strong>on</strong>s coming into being in a particular social and historical c<strong>on</strong>text while other possible<br />

c<strong>on</strong>juncti<strong>on</strong>s do not, raise comm<strong>on</strong> sets of issues. These c<strong>on</strong>diti<strong>on</strong>s include both natural<br />

c<strong>on</strong>straints and voluntary choices (even if those choices are not always recognised or explicit).<br />

Such choices depend <strong>on</strong> complex judgments involving values, beliefs and expectati<strong>on</strong>s about the<br />

technologies and their uses. How these choices are made – how different values, beliefs and<br />

expectati<strong>on</strong>s are drawn in, evaluated, incorporated or excluded – just as much as the nature of<br />

the c<strong>on</strong>siderati<strong>on</strong>s involved, have important ethical and political dimensi<strong>on</strong>s. Just as choosing the<br />

c<strong>on</strong>diti<strong>on</strong>s governing emergence is a comm<strong>on</strong> issue for <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> it may be equally<br />

comm<strong>on</strong> to other, n<strong>on</strong>-biological technologies. Several c<strong>on</strong>siderati<strong>on</strong>s, however, make<br />

<str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> a particularly appropriate and timely focus.<br />

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