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Emerging biotechnologies: full report - Nuffield Council on Bioethics

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E m e r g i n g b i o t e c h n o l o g i e s<br />

Chapter 6 - Research<br />

Chapter overview<br />

In this Chapter we examine the role played by researchers in shaping the emergence of <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>. We examine the<br />

influences of researchers <strong>on</strong> biotechnology trajectories and the influences <strong>on</strong> researchers that govern how their influence<br />

is brought to bear. We c<strong>on</strong>sider two extreme views (that researchers themselves determine the directi<strong>on</strong> of their research<br />

and that researchers are merely instruments in society’s attempts to achieve goals through science and technology) and<br />

ask how the changing relati<strong>on</strong>ship between science and society may rebalance the positi<strong>on</strong> of researchers between these<br />

two extremes. We also discuss the way in which this balance is struck in the UK’s current arrangements for funding<br />

academic research through the research councils, and how industry visi<strong>on</strong>s influence the directi<strong>on</strong> of publicly funded<br />

research through road-mapping exercises.<br />

We also c<strong>on</strong>sider the influence <strong>on</strong> researchers of powerful imaginaries encapsulated in ‘grand challenges’ and argue that<br />

in framing these the broadest range of views should be involved in accordance with the principles we set out in Chapter 4,<br />

to avoid an over-emphasis <strong>on</strong> technological soluti<strong>on</strong>s to problems with substantial social dimensi<strong>on</strong>s. We then c<strong>on</strong>sider<br />

the effect <strong>on</strong> research of the need to dem<strong>on</strong>strate ‘impact’ to potential funders and c<strong>on</strong>clude that this can encourage a<br />

tendency to ‘overpromise’ in relati<strong>on</strong> to the benefits of emerging biotechnology in a way that is not supported by the<br />

science.<br />

Finally, we discuss the role of researchers as public figures, communicating research to a wider audience and informing<br />

public decisi<strong>on</strong> making and the resp<strong>on</strong>sibilities that this entails, including c<strong>on</strong>siderati<strong>on</strong> of how others, such as DIYbio<br />

practiti<strong>on</strong>ers and social scientists might enrich the practices of professi<strong>on</strong>al research.<br />

Introducti<strong>on</strong><br />

6.1 This Chapter focuses <strong>on</strong> the role of researchers in steering the development of emerging<br />

<str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>. Researchers do not form a homogenous group but are subject to different<br />

motivati<strong>on</strong>s, pressures and influences, including the kind of instituti<strong>on</strong> in which they work and<br />

the sources of their funding. There are perceived tensi<strong>on</strong>s between the ‘basic research’ missi<strong>on</strong><br />

of researchers in academic laboratories and the applied purposes of research carried out in<br />

more commercial envir<strong>on</strong>ments, but simple distincti<strong>on</strong>s between basic and applied research are<br />

inadequate to account for the diversity of motivati<strong>on</strong>s and external pressures to which<br />

researchers are subject. 368<br />

6.2 We also acknowledge the different roles of researchers both as influencers and as subject to<br />

influences coming directly from funders, indirectly from the wider socio-political envir<strong>on</strong>ment,<br />

and from the emerging tendencies of the scientific enterprise as a whole. We recognise a<br />

paradox in the lack of agency of individual researchers despite their centrality in the research<br />

enterprise.<br />

6.3 The questi<strong>on</strong>s that guide this Chapter are: what decisi<strong>on</strong>s determine the directi<strong>on</strong> of research in<br />

emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>? How does the framing of these decisi<strong>on</strong>s about research priorities<br />

and trajectories get closed down? How can decisi<strong>on</strong>s be opened up to social and ethical<br />

values? And how can we steer the research system to maximise the c<strong>on</strong>tributi<strong>on</strong> of research <strong>on</strong><br />

emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> to the public good?<br />

Where is research <strong>on</strong> emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> d<strong>on</strong>e?<br />

6.4 It is extremely difficult to identify where research <strong>on</strong> emerging <str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g> is carried out,<br />

due to the paucity of data available or its ambiguity. Some informati<strong>on</strong> can be gleaned from<br />

papers published in journals, from research grants awarded, and from <str<strong>on</strong>g>report</str<strong>on</strong>g>ed informati<strong>on</strong><br />

about ec<strong>on</strong>omic activity surrounding research. However, as is perhaps to be expected in any<br />

emerging field, the categorisati<strong>on</strong>s are not sufficiently precise and c<strong>on</strong>sistent, and not used<br />

sufficiently precisely or c<strong>on</strong>sistently, to allow meaningful comparis<strong>on</strong> or aggregati<strong>on</strong>. 369<br />

368 Calvert J (2006) What’s special about basic research? Science, Technology & Human Values 31: 199-220.<br />

369 The limitati<strong>on</strong>s are documented in research commissi<strong>on</strong>ed for this project from Dr Michael Hopkins and available via the<br />

<str<strong>on</strong>g>Council</str<strong>on</strong>g>’s website. See: www.nuffieldbiothics.org/emerging-<str<strong>on</strong>g>biotechnologies</str<strong>on</strong>g>-evidence-reviews.<br />

94

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