The ethics of research involving animals - Nuffield Council on ...
The ethics of research involving animals - Nuffield Council on ...
The ethics of research involving animals - Nuffield Council on ...
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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />
Box 3.3: Three paradigms <str<strong>on</strong>g>of</str<strong>on</strong>g> normative <str<strong>on</strong>g>ethics</str<strong>on</strong>g><br />
Normative theory is a branch <str<strong>on</strong>g>of</str<strong>on</strong>g> philosophical <str<strong>on</strong>g>ethics</str<strong>on</strong>g><br />
which seeks to develop theoretical frameworks that can<br />
help to determine whether acti<strong>on</strong>s are right or wr<strong>on</strong>g.<br />
Three important approaches are c<strong>on</strong>sequentialism,<br />
de<strong>on</strong>tology and virtue <str<strong>on</strong>g>ethics</str<strong>on</strong>g>. Some take the view that<br />
they are mutually exclusive, and c<strong>on</strong>stitute competing<br />
frameworks. Others point out that they can be seen as<br />
overlapping and complementary, emphasising different<br />
aspects <str<strong>on</strong>g>of</str<strong>on</strong>g> the complex interacti<strong>on</strong>s <str<strong>on</strong>g>of</str<strong>on</strong>g> humans between<br />
each other and with the envir<strong>on</strong>ment.<br />
C<strong>on</strong>sequentialism<br />
According to this approach, the moral value <str<strong>on</strong>g>of</str<strong>on</strong>g> individual<br />
human acti<strong>on</strong>s, or rules for such acti<strong>on</strong>s, is determined<br />
primarily by their outcome. Such approaches do not<br />
usually put str<strong>on</strong>g emphasis <strong>on</strong> the inviolable rights <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
moral agents or moral subjects. One important type <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
c<strong>on</strong>sequentialism is utilitarianism, developed most<br />
prominently by the British philosophers Jeremy Bentham<br />
and John Stuart Mill in the 18th and 19th centuries.* For<br />
utilitarians, the best acti<strong>on</strong>s are those that produce most<br />
overall happiness or pleasure (see paragraphs 3.52–3.55).<br />
De<strong>on</strong>tology<br />
<str<strong>on</strong>g>The</str<strong>on</strong>g> name <str<strong>on</strong>g>of</str<strong>on</strong>g> this theory is derived from the Greek de<strong>on</strong>,<br />
which means duty or obligati<strong>on</strong>. In this theory, certain<br />
acti<strong>on</strong>s are right or wr<strong>on</strong>g independent <str<strong>on</strong>g>of</str<strong>on</strong>g> their outcome.<br />
Instead, their rightness or wr<strong>on</strong>gness is defined by a<br />
formal system, which defines certain acti<strong>on</strong>s as<br />
intrinsically right or wr<strong>on</strong>g. Moral agents have a duty to<br />
respect the principles derived from this system and to act<br />
according to it. Rights <str<strong>on</strong>g>of</str<strong>on</strong>g> other moral agents or subjects<br />
can be violated if they are not treated accordingly.<br />
Historically, de<strong>on</strong>tology is associated with the work <str<strong>on</strong>g>of</str<strong>on</strong>g> the<br />
German philosopher Immanuel Kant (1724–1804; see<br />
paragraphs 3.56–3.57).† A separate form <str<strong>on</strong>g>of</str<strong>on</strong>g> de<strong>on</strong>tology<br />
advocates the c<strong>on</strong>cept <str<strong>on</strong>g>of</str<strong>on</strong>g> animal rights (see Box 3.4).<br />
Virtue <str<strong>on</strong>g>ethics</str<strong>on</strong>g><br />
According to this approach, first developed by early<br />
philosophers such as Aristotle around 2,300 years ago,<br />
moral value depends less <strong>on</strong> the duty to follow rules given<br />
by formal systems, or <strong>on</strong> the duty to maximise beneficial<br />
c<strong>on</strong>sequences, than <strong>on</strong> the character <str<strong>on</strong>g>of</str<strong>on</strong>g> the moral agent.<br />
A virtuous moral agent is some<strong>on</strong>e who deliberates and<br />
acts in a way which displays virtues such as justice,<br />
truthfulness and courage. According to this view, morality<br />
is closer to the exercise <str<strong>on</strong>g>of</str<strong>on</strong>g> a skill than the following <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
standardised formulae or rules.‡<br />
* See Sinnott-Armstr<strong>on</strong>g W (2003) C<strong>on</strong>sequentialism, available<br />
at: http://plato.stanford.edu/entries/c<strong>on</strong>sequentialism/.<br />
Accessed <strong>on</strong>: 18 Apr 2005.<br />
† See Johns<strong>on</strong> R (2004) Kant’s Moral Philosophy, available at:<br />
http://plato.stanford.edu/entries/kant-moral/. Accessed <strong>on</strong>: 19<br />
Apr 2005.<br />
‡ See Kraut R (2001) Aristotle’s Ethics, available at:<br />
http://plato.stanford.edu/entries/aristotle-<str<strong>on</strong>g>ethics</str<strong>on</strong>g>/. Accessed <strong>on</strong>:<br />
18 Apr 2005.<br />
C<strong>on</strong>sequentialism<br />
3.52 In any approach that seeks to weigh c<strong>on</strong>sequences, a number <str<strong>on</strong>g>of</str<strong>on</strong>g> more detailed questi<strong>on</strong>s<br />
need to be c<strong>on</strong>sidered, to establish whether justificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> a particular form <str<strong>on</strong>g>of</str<strong>on</strong>g> animal<br />
<str<strong>on</strong>g>research</str<strong>on</strong>g> is possible. <str<strong>on</strong>g>The</str<strong>on</strong>g>se are as follows:<br />
i) <str<strong>on</strong>g>The</str<strong>on</strong>g> value <str<strong>on</strong>g>of</str<strong>on</strong>g> the goals <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>:<br />
Research may be undertaken to achieve various goals, for example to advance basic<br />
biological knowledge, or to directly improve medical practice. In evaluating <str<strong>on</strong>g>research</str<strong>on</strong>g>, it is<br />
important to ask: how valuable is the goal and for whom? How speculative might the gain<br />
be? (See paragraphs 3.9-3.19 and 5.4).<br />
CHAPTER 3 ETHICAL ISSUES RAISED BY ANIMAL RESEARCH<br />
ii) <str<strong>on</strong>g>The</str<strong>on</strong>g> degree <str<strong>on</strong>g>of</str<strong>on</strong>g> harm experienced by <str<strong>on</strong>g>animals</str<strong>on</strong>g>:<br />
This is dependent <strong>on</strong> the number <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> used, and their capacity to experience pain,<br />
suffering or distress or other adverse effects. <str<strong>on</strong>g>The</str<strong>on</strong>g> degree <str<strong>on</strong>g>of</str<strong>on</strong>g> harm relates, where applicable,<br />
to c<strong>on</strong>diti<strong>on</strong>s during breeding, transport, housing and <str<strong>on</strong>g>research</str<strong>on</strong>g>-related procedures<br />
(paragraphs 4.31-4.59). <str<strong>on</strong>g>The</str<strong>on</strong>g> questi<strong>on</strong> posed is: what harm could <str<strong>on</strong>g>animals</str<strong>on</strong>g> suffer in pursuit <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
the <str<strong>on</strong>g>research</str<strong>on</strong>g> goals?<br />
iii) <str<strong>on</strong>g>The</str<strong>on</strong>g> availability <str<strong>on</strong>g>of</str<strong>on</strong>g> alternatives to <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>:<br />
Are there n<strong>on</strong>-animal alternatives that could achieve the same <str<strong>on</strong>g>research</str<strong>on</strong>g> goal? If alternatives are<br />
not available, it would appear important to be able to assess the reas<strong>on</strong>s why: are alternatives<br />
logically or c<strong>on</strong>ceptually unavailable, or are they unavailable because <str<strong>on</strong>g>of</str<strong>on</strong>g> political, financial,<br />
logistical or other practical reas<strong>on</strong>s? (See paragraphs 3.63-3.66 and Chapter 11).<br />
3.53 Before examining c<strong>on</strong>sequentialism in more detail, we need to discuss a special issue raised<br />
by point i) above, regarding the value <str<strong>on</strong>g>of</str<strong>on</strong>g> the goal(s) <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>. Some people argue that a<br />
major distincti<strong>on</strong> should be made between two types <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>. <str<strong>on</strong>g>The</str<strong>on</strong>g>y note that there is (a)<br />
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