The ethics of research involving animals - Nuffield Council on ...
The ethics of research involving animals - Nuffield Council on ...
The ethics of research involving animals - Nuffield Council on ...
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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />
pharmaceutical companies to maximise commercial revenue. 7 Lastly, as we observed above,<br />
pharmaceutical <str<strong>on</strong>g>research</str<strong>on</strong>g> accounts for approximately <strong>on</strong>e third <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> used. Research is<br />
also undertaken in the c<strong>on</strong>text <str<strong>on</strong>g>of</str<strong>on</strong>g> basic <str<strong>on</strong>g>research</str<strong>on</strong>g> (30%, see Chapter 5) and toxicity testing<br />
(16%, see Chapter 9), which require different kinds <str<strong>on</strong>g>of</str<strong>on</strong>g> justificati<strong>on</strong> (paragraph 3.53).<br />
‘Engaging in <str<strong>on</strong>g>research</str<strong>on</strong>g> is a part <str<strong>on</strong>g>of</str<strong>on</strong>g> human nature’<br />
3.15 We need to c<strong>on</strong>sider <strong>on</strong>e further argument that is relevant to our explorati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the need<br />
for the justificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> animal <str<strong>on</strong>g>research</str<strong>on</strong>g>. Some people assert that it is an essential trait <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
humans to strive for knowledge through methodological enquiry. Hence, independent <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
the value <str<strong>on</strong>g>of</str<strong>on</strong>g> the results <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>, it could be argued that <str<strong>on</strong>g>research</str<strong>on</strong>g> activity itself holds<br />
significant intrinsic value. For those who hold this view, undertaking <str<strong>on</strong>g>research</str<strong>on</strong>g>, including that<br />
<str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>, can be equated with the value <str<strong>on</strong>g>of</str<strong>on</strong>g> foraging for apes and nest-building for<br />
birds. <str<strong>on</strong>g>The</str<strong>on</strong>g>y might therefore argue that it would be wr<strong>on</strong>g to expect humans to cease<br />
undertaking animal <str<strong>on</strong>g>research</str<strong>on</strong>g>, because it is part <str<strong>on</strong>g>of</str<strong>on</strong>g> their natural behaviour.<br />
3.16 Arguments based <strong>on</strong> ‘naturalness’ have c<strong>on</strong>siderable currency in the debate about animal<br />
<str<strong>on</strong>g>research</str<strong>on</strong>g>. However, there is disagreement about the usefulness <str<strong>on</strong>g>of</str<strong>on</strong>g> noti<strong>on</strong>s <str<strong>on</strong>g>of</str<strong>on</strong>g> naturalness<br />
(paragraphs 3.24–3.26). It is also questi<strong>on</strong>able whether the alleged natural drive for humans<br />
to undertake <str<strong>on</strong>g>research</str<strong>on</strong>g> and advance knowledge would be irredeemably frustrated if they<br />
refrained from using <str<strong>on</strong>g>animals</str<strong>on</strong>g>. One resp<strong>on</strong>dent to the C<strong>on</strong>sultati<strong>on</strong> observed that ‘necessity<br />
is the mother <str<strong>on</strong>g>of</str<strong>on</strong>g> inventi<strong>on</strong>’, and hence it could be argued that if there was a political will<br />
not to use <str<strong>on</strong>g>animals</str<strong>on</strong>g>, human creativity might produce other soluti<strong>on</strong>s to achieve the same<br />
<str<strong>on</strong>g>research</str<strong>on</strong>g> goals.<br />
3.17 It would appear that arguments about the loss <str<strong>on</strong>g>of</str<strong>on</strong>g> opportunities in both scientific <str<strong>on</strong>g>research</str<strong>on</strong>g> and<br />
gaining knowledge would <strong>on</strong>ly be forceful where, for compelling logical, ethical or pragmatic<br />
reas<strong>on</strong>s, there was no possibility to obtain specific informati<strong>on</strong> using n<strong>on</strong>-animal methods<br />
(see paragraphs 3.63–3.66). For example, it could be c<strong>on</strong>tended that it would be neither<br />
pragmatically feasible nor ethically permissible to produce inbred strains <str<strong>on</strong>g>of</str<strong>on</strong>g> humans for<br />
genetic knock-out studies (see paragraph 5.20). However, in an ethical discussi<strong>on</strong> we might<br />
ask what exactly are the reas<strong>on</strong>s that appear to make it ethically permissible to use mice, but<br />
ethically wr<strong>on</strong>g to use humans, for genetic knock-out studies. We therefore now turn to the<br />
sec<strong>on</strong>d questi<strong>on</strong> introduced in paragraph 3.10.<br />
CHAPTER 3 ETHICAL ISSUES RAISED BY ANIMAL RESEARCH<br />
Why should the use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> in <str<strong>on</strong>g>research</str<strong>on</strong>g> be acceptable in cases where it would be unacceptable<br />
to use humans?<br />
3.18 Several resp<strong>on</strong>dents to the C<strong>on</strong>sultati<strong>on</strong> expressed their c<strong>on</strong>cerns about the view that<br />
c<strong>on</strong>venience or scientific necessity are sometimes seen as sufficient reas<strong>on</strong>s for using <str<strong>on</strong>g>animals</str<strong>on</strong>g><br />
in <str<strong>on</strong>g>research</str<strong>on</strong>g>:<br />
‘I feel that any living creature should be given the same level <str<strong>on</strong>g>of</str<strong>on</strong>g> compassi<strong>on</strong> as any other.<br />
Thus if it is unacceptable to c<strong>on</strong>duct <str<strong>on</strong>g>research</str<strong>on</strong>g> <strong>on</strong> a human being, I feel that it is also<br />
unacceptable to c<strong>on</strong>duct said <str<strong>on</strong>g>research</str<strong>on</strong>g> <strong>on</strong> any other living creature…’<br />
Gaynor Armitage<br />
‘We believe that all living things have the same moral status.’<br />
Claire Hardman and Tom Schoeffler<br />
‘a) Animals are not like us. But then the informati<strong>on</strong> gleaned from <str<strong>on</strong>g>research</str<strong>on</strong>g> c<strong>on</strong>ducted<br />
<str<strong>on</strong>g>involving</str<strong>on</strong>g> them would not be useful to humans, so<br />
b) Animals are like us. Which makes it ethically wr<strong>on</strong>g to involve them in <str<strong>on</strong>g>research</str<strong>on</strong>g>.’<br />
Kate White<br />
37