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The ethics of research involving animals - Nuffield Council on ...

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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />

Ethical issues raised by animal <str<strong>on</strong>g>research</str<strong>on</strong>g><br />

Introducti<strong>on</strong><br />

3.1 As we have said, the debate about <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> ranges broadly over two<br />

distinct questi<strong>on</strong>s. <str<strong>on</strong>g>The</str<strong>on</strong>g> first asks whether animal <str<strong>on</strong>g>research</str<strong>on</strong>g> yields useful knowledge that could<br />

not be gained from other sources. <str<strong>on</strong>g>The</str<strong>on</strong>g> sec<strong>on</strong>d c<strong>on</strong>cerns whether it is morally acceptable for<br />

humans to use <str<strong>on</strong>g>animals</str<strong>on</strong>g> in ways that can cause them harm. <str<strong>on</strong>g>The</str<strong>on</strong>g>se two questi<strong>on</strong>s are clearly<br />

related: if it were the case that we learn nothing useful and distinctive from <str<strong>on</strong>g>research</str<strong>on</strong>g> that<br />

may harm <str<strong>on</strong>g>animals</str<strong>on</strong>g>, it would be difficult to see how, <strong>on</strong> any reas<strong>on</strong>able view, it could be<br />

morally justified. <str<strong>on</strong>g>The</str<strong>on</strong>g> questi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> scientific justificati<strong>on</strong> is therefore fundamental to the<br />

questi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> moral justificati<strong>on</strong> and we explore it in detail in Chapters 5–10.<br />

3.2 However, a positive answer to the scientific questi<strong>on</strong> does not settle the moral questi<strong>on</strong>, for<br />

it may be the case that an experiment that yields useful and relevant informati<strong>on</strong> is not<br />

ethically acceptable. We need therefore to c<strong>on</strong>sider from first principles the arguments in<br />

support <str<strong>on</strong>g>of</str<strong>on</strong>g>, and against, <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>. For the purpose <str<strong>on</strong>g>of</str<strong>on</strong>g> our discussi<strong>on</strong>, we<br />

take the principal ethical questi<strong>on</strong>s to be the following:<br />

■ Provided there are substantial benefits associated with animal <str<strong>on</strong>g>research</str<strong>on</strong>g>, why should the<br />

use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> require special justificati<strong>on</strong>?<br />

■ Can any use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> by humans be justified? Which specific issues need to be<br />

c<strong>on</strong>sidered in the case <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>?<br />

■ What role does the unavailability <str<strong>on</strong>g>of</str<strong>on</strong>g> alternatives play in the justificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g><br />

<str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>?<br />

■ How does the justificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> such <str<strong>on</strong>g>research</str<strong>on</strong>g> relate to the justificati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> other uses, such<br />

as food producti<strong>on</strong>?<br />

■ What is the appropriate role <str<strong>on</strong>g>of</str<strong>on</strong>g> regulati<strong>on</strong> for <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>?<br />

3.3 For each <str<strong>on</strong>g>of</str<strong>on</strong>g> these questi<strong>on</strong>s, we c<strong>on</strong>sider comm<strong>on</strong>ly encountered arguments to bring clarity<br />

to the debate; to identify agreement where it exists; and to understand what lies behind<br />

remaining disagreement. We hope that this approach will be useful in enabling readers to<br />

make informed judgements about whether or not specific types <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>, as described in<br />

Chapters 5–9, can be justified. We would also like to encourage them to reflect up<strong>on</strong> the<br />

assumpti<strong>on</strong>s behind their own positi<strong>on</strong>s and those <str<strong>on</strong>g>of</str<strong>on</strong>g> others.<br />

CHAPTER 3 ETHICAL ISSUES RAISED BY ANIMAL RESEARCH<br />

Facts, values and the reflective equilibrium<br />

3.4 Historically, a number <str<strong>on</strong>g>of</str<strong>on</strong>g> apparently rigid and irrec<strong>on</strong>cilable implicit and explicit ethical<br />

positi<strong>on</strong>s <strong>on</strong> animal <str<strong>on</strong>g>research</str<strong>on</strong>g> have arisen. Often, holders <str<strong>on</strong>g>of</str<strong>on</strong>g> these views think that their<br />

ethical judgement is irrefutably right, while that <str<strong>on</strong>g>of</str<strong>on</strong>g> others is simply wr<strong>on</strong>g. C<strong>on</strong>sequently,<br />

they c<strong>on</strong>sider truths about animal <str<strong>on</strong>g>research</str<strong>on</strong>g> to be self-evident, and suspect those who do not<br />

share these views <str<strong>on</strong>g>of</str<strong>on</strong>g> some sort <str<strong>on</strong>g>of</str<strong>on</strong>g> ‘moral astigmatism’ or intenti<strong>on</strong>al malevolence.<br />

3.5 This state <str<strong>on</strong>g>of</str<strong>on</strong>g> affairs raises complex philosophical issues that are usually debated under the<br />

title <str<strong>on</strong>g>of</str<strong>on</strong>g> moral epistemology. <str<strong>on</strong>g>The</str<strong>on</strong>g> term refers to the study <str<strong>on</strong>g>of</str<strong>on</strong>g>, am<strong>on</strong>g other things, whether<br />

and how we can come to know moral truths; what we mean when we make moral<br />

judgements; and under what c<strong>on</strong>diti<strong>on</strong>s we can change the moral judgements <str<strong>on</strong>g>of</str<strong>on</strong>g> others. 1<br />

Although this Report is not suited to a detailed explorati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the many subtleties that<br />

1 See Campbell R (2003) Stanford Encyclopaedia <str<strong>on</strong>g>of</str<strong>on</strong>g> Philosophy: Moral epistemology, available at:<br />

http://plato.stanford.edu/entries/moral-epistemology. Accessed <strong>on</strong>: 11 Apr 2005.<br />

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