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The ethics of research involving animals - Nuffield Council on ...

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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />

other uses <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>. Awareness that c<strong>on</strong>tradictory views are <str<strong>on</strong>g>of</str<strong>on</strong>g>ten held simultaneously is<br />

an important first step in c<strong>on</strong>sidering the ethical issues raised by <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>.<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g> benefits <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g><br />

15.5 Historically, <str<strong>on</strong>g>animals</str<strong>on</strong>g> have been used in a wide range <str<strong>on</strong>g>of</str<strong>on</strong>g> scientific <str<strong>on</strong>g>research</str<strong>on</strong>g> activities that<br />

have provided many benefits to society, particularly in relati<strong>on</strong> to the advancement <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

scientific knowledge, human and veterinary medicine and the safety <str<strong>on</strong>g>of</str<strong>on</strong>g> chemical products.<br />

15.6 Some <str<strong>on</strong>g>of</str<strong>on</strong>g> these advances might have been achieved by other means, although we cannot<br />

know this. Neither can we know what a world would look like in which animal <str<strong>on</strong>g>research</str<strong>on</strong>g> had<br />

never been undertaken. Hypothetically, there may have been other opti<strong>on</strong>s that could have<br />

produced acceptable levels <str<strong>on</strong>g>of</str<strong>on</strong>g> knowledge and healthcare. <str<strong>on</strong>g>The</str<strong>on</strong>g>se levels might have been lower<br />

than our current standards, but perhaps if society had deemed the use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> for <str<strong>on</strong>g>research</str<strong>on</strong>g><br />

as unacceptable there would have been acceptance <str<strong>on</strong>g>of</str<strong>on</strong>g> greater limitati<strong>on</strong>s <strong>on</strong> scientific and<br />

medical progress. Alternatively, it is c<strong>on</strong>ceivable that equally good or better progress might<br />

have been achieved with other methods. <str<strong>on</strong>g>The</str<strong>on</strong>g> Working Party agreed that speculati<strong>on</strong> about<br />

whether or not acceptable standards in basic and applied <str<strong>on</strong>g>research</str<strong>on</strong>g> could have been achieved<br />

in the past by means other than the use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> is less important than the questi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

assessing the c<strong>on</strong>sequences <str<strong>on</strong>g>of</str<strong>on</strong>g> c<strong>on</strong>tinuing or aband<strong>on</strong>ing animal experimentati<strong>on</strong> now.<br />

15.7 It is sometimes assumed that to end animal <str<strong>on</strong>g>research</str<strong>on</strong>g> would be to end scientific and medical<br />

progress, but such generalisati<strong>on</strong> is unhelpful. <str<strong>on</strong>g>The</str<strong>on</strong>g> UK Government has resp<strong>on</strong>ded to<br />

changes in the moral climate by introducing policies that have ended some types <str<strong>on</strong>g>of</str<strong>on</strong>g> animal<br />

<str<strong>on</strong>g>research</str<strong>on</strong>g> and testing in the UK. For example the use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> for the testing <str<strong>on</strong>g>of</str<strong>on</strong>g> cosmetic<br />

products and their ingredients, alcohol and tobacco has ceased. Similar policies are in place<br />

regarding the use <str<strong>on</strong>g>of</str<strong>on</strong>g> the great apes. Independent <str<strong>on</strong>g>of</str<strong>on</strong>g> the moral acceptability <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>,<br />

the scientific costs and benefits <str<strong>on</strong>g>of</str<strong>on</strong>g> aband<strong>on</strong>ing specific types <str<strong>on</strong>g>of</str<strong>on</strong>g> animal <str<strong>on</strong>g>research</str<strong>on</strong>g> need to be<br />

assessed <strong>on</strong> a case by case basis. On the <strong>on</strong>e hand, the possibility <str<strong>on</strong>g>of</str<strong>on</strong>g> the emergence <str<strong>on</strong>g>of</str<strong>on</strong>g> new<br />

diseases may require a reassessment <str<strong>on</strong>g>of</str<strong>on</strong>g> whether the aband<strong>on</strong>ment <str<strong>on</strong>g>of</str<strong>on</strong>g> specific types <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

<str<strong>on</strong>g>research</str<strong>on</strong>g> is still justified. On the other, scientific advances that could replace the use <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

<str<strong>on</strong>g>animals</str<strong>on</strong>g> in some areas may enjoin us to assess whether further policies should be introduced<br />

to terminate these uses <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> accordingly.<br />

15.8 <str<strong>on</strong>g>The</str<strong>on</strong>g> validity, usefulness and relevance <str<strong>on</strong>g>of</str<strong>on</strong>g> specific types <str<strong>on</strong>g>of</str<strong>on</strong>g> animal <str<strong>on</strong>g>research</str<strong>on</strong>g>, for example in<br />

relati<strong>on</strong> to the use <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> for the study <str<strong>on</strong>g>of</str<strong>on</strong>g> human diseases, needs to be ascertained in<br />

each individual case.<br />

Desirability <str<strong>on</strong>g>of</str<strong>on</strong>g> a world without animal <str<strong>on</strong>g>research</str<strong>on</strong>g><br />

15.9 All <str<strong>on</strong>g>research</str<strong>on</strong>g> licensed in the UK under the A(SP)A has the potential to cause pain, suffering,<br />

distress or lasting harm to the <str<strong>on</strong>g>animals</str<strong>on</strong>g> used. Most <str<strong>on</strong>g>animals</str<strong>on</strong>g> are killed at the end <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

experiments. A world in which the important benefits <str<strong>on</strong>g>of</str<strong>on</strong>g> such <str<strong>on</strong>g>research</str<strong>on</strong>g> could be achieved<br />

without causing pain, suffering, distress, lasting harm or death to <str<strong>on</strong>g>animals</str<strong>on</strong>g> involved in<br />

<str<strong>on</strong>g>research</str<strong>on</strong>g> must be the ultimate goal.<br />

15.10 We have c<strong>on</strong>sidered the different arguments advanced in favour <str<strong>on</strong>g>of</str<strong>on</strong>g> and against c<strong>on</strong>tinuing<br />

specific types <str<strong>on</strong>g>of</str<strong>on</strong>g> animal <str<strong>on</strong>g>research</str<strong>on</strong>g> in Chapters 3 and 14. Some believe the imperative to<br />

protect animal welfare should be overriding, whereas others believe that the moral<br />

arguments favour the c<strong>on</strong>tinuati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g> <strong>on</strong> <str<strong>on</strong>g>animals</str<strong>on</strong>g>. All members <str<strong>on</strong>g>of</str<strong>on</strong>g> the Working<br />

Party acknowledged that these viewpoints arise from moral c<strong>on</strong>victi<strong>on</strong>s that should be<br />

given serious c<strong>on</strong>siderati<strong>on</strong>. This approach requires open-mindedness in trying to<br />

understand the reas<strong>on</strong>s and arguments <str<strong>on</strong>g>of</str<strong>on</strong>g> others. Genuine willingness is also required to<br />

test and, where necessary, revise <strong>on</strong>e’s own moral framework.<br />

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