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The ethics of research involving animals - Nuffield Council on ...

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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />

Discussi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> ethical issues<br />

Introducti<strong>on</strong><br />

14.1 In this chapter we resume the discussi<strong>on</strong> about ethical issues raised by <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g><br />

<str<strong>on</strong>g>animals</str<strong>on</strong>g>. We also c<strong>on</strong>sider basic questi<strong>on</strong>s about how public policy should be shaped in this<br />

area where there is widespread disagreement am<strong>on</strong>g members <str<strong>on</strong>g>of</str<strong>on</strong>g> the UK populati<strong>on</strong>. In<br />

Chapter 3 we argued that the ethical questi<strong>on</strong> is best thought <str<strong>on</strong>g>of</str<strong>on</strong>g> not simply in terms <str<strong>on</strong>g>of</str<strong>on</strong>g> the<br />

relative moral status <str<strong>on</strong>g>of</str<strong>on</strong>g> humans and <str<strong>on</strong>g>animals</str<strong>on</strong>g>, but by c<strong>on</strong>siderati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> two questi<strong>on</strong>s: first,<br />

what features <str<strong>on</strong>g>of</str<strong>on</strong>g> human and <str<strong>on</strong>g>animals</str<strong>on</strong>g> make them objects <str<strong>on</strong>g>of</str<strong>on</strong>g> moral c<strong>on</strong>cern; and sec<strong>on</strong>d,<br />

how should those features be taken into account in moral reas<strong>on</strong>ing: through weighing <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

factors or through the generati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> absolute prohibiti<strong>on</strong>s?<br />

14.2 We suggested that there are five features that have the potential to give rise to moral c<strong>on</strong>cern:<br />

sentience; higher cognitive capacities; capability for flourishing; sociability; and possessi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> a<br />

life (paragraphs 3.27–3.50). <str<strong>on</strong>g>The</str<strong>on</strong>g> last <str<strong>on</strong>g>of</str<strong>on</strong>g> these was the most c<strong>on</strong>troversial. We also explored how<br />

to c<strong>on</strong>sider these features in moral reas<strong>on</strong>ing. A c<strong>on</strong>sequentialist view weighs all costs against<br />

all benefits (paragraphs 3.52–3.55). A de<strong>on</strong>tological view lays down particular prohibiti<strong>on</strong>s<br />

(paragraphs 3.56–3.57). A hybrid view c<strong>on</strong>tains some prohibiti<strong>on</strong>s and some weighing<br />

(paragraphs 3.58–3.62). We also c<strong>on</strong>cluded that the ethical positi<strong>on</strong>s that coincide with the<br />

current UK regulati<strong>on</strong>s are hybrid (paragraph 3.58). It appears that, in practice, the positi<strong>on</strong>s<br />

<str<strong>on</strong>g>of</str<strong>on</strong>g> most people, except perhaps those <str<strong>on</strong>g>of</str<strong>on</strong>g> animal protecti<strong>on</strong> groups, are hybrid too, allowing<br />

some weighing <str<strong>on</strong>g>of</str<strong>on</strong>g> factors, and accepting absolute prohibiti<strong>on</strong>s in other areas. 1<br />

CHAPTER 14 DISCUSSION OF ETHICAL ISSUES<br />

14.3 If we accept that most views are hybrid, then we can see that the debate comes down to<br />

disagreement <strong>on</strong> two questi<strong>on</strong>s: first, what are the absolute c<strong>on</strong>straints? and sec<strong>on</strong>dly, how<br />

do we weigh different morally relevant factors within the permitted area? To answer these<br />

questi<strong>on</strong>s, we will always need to c<strong>on</strong>sider at least five questi<strong>on</strong>s:<br />

i) what are the goals <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g>?<br />

ii)<br />

what is the probability <str<strong>on</strong>g>of</str<strong>on</strong>g> success?<br />

iii) which <str<strong>on</strong>g>animals</str<strong>on</strong>g> are to be used?<br />

iv) what effect will there be <strong>on</strong> the <str<strong>on</strong>g>animals</str<strong>on</strong>g> used in the experiment?<br />

v) are there any alternatives?<br />

14.4 To bring the basic moral issues into sharp focus, we c<strong>on</strong>sider first, as a purely hypothetical<br />

example, an abstracti<strong>on</strong> that might be c<strong>on</strong>sidered by many people as a relatively<br />

unc<strong>on</strong>troversial type <str<strong>on</strong>g>of</str<strong>on</strong>g> animal experiment. We assume that the goal <str<strong>on</strong>g>of</str<strong>on</strong>g> the <str<strong>on</strong>g>research</str<strong>on</strong>g> is the<br />

saving <str<strong>on</strong>g>of</str<strong>on</strong>g> human life through the eradicati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> a widespread painful and debilitating<br />

childhood disease; that there is a high probability <str<strong>on</strong>g>of</str<strong>on</strong>g> success; that the experiments can be<br />

c<strong>on</strong>ducted <strong>on</strong> a small number <str<strong>on</strong>g>of</str<strong>on</strong>g> mice; that the <str<strong>on</strong>g>animals</str<strong>on</strong>g> will suffer <strong>on</strong>ly mild discomfort,<br />

although they will have shortened lives; and that no acceptable alternatives will be<br />

available in the foreseeable future however much effort we expend. What objecti<strong>on</strong>s could<br />

there be, if all these c<strong>on</strong>diti<strong>on</strong>s are met?<br />

14.5 In c<strong>on</strong>sidering the example it is important to be aware that it has been drawn up in such a<br />

way that the total benefits <str<strong>on</strong>g>of</str<strong>on</strong>g> the experiment (to humans) are in some sense greater than<br />

1 Even some <str<strong>on</strong>g>of</str<strong>on</strong>g> those opposed in general to animal <str<strong>on</strong>g>research</str<strong>on</strong>g> may allow that some <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> is permissible; for<br />

example n<strong>on</strong>-harmful observati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> in their natural habitat for the purpose <str<strong>on</strong>g>of</str<strong>on</strong>g> c<strong>on</strong>servati<strong>on</strong>, and possibly mildly<br />

harmful <str<strong>on</strong>g>research</str<strong>on</strong>g> that entails tagging or ringing <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>.<br />

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