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The ethics of research involving animals - Nuffield Council on ...

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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />

We c<strong>on</strong>clude that some form <str<strong>on</strong>g>of</str<strong>on</strong>g> regulati<strong>on</strong> is necessary for good moral practice, but that it is<br />

crucial to be aware that it may not be sufficient (paragraph 3.77).<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g> views <str<strong>on</strong>g>of</str<strong>on</strong>g> the members <str<strong>on</strong>g>of</str<strong>on</strong>g> the Working Party<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g>re is no c<strong>on</strong>sensus within the Working Party as to whether <strong>on</strong>e <str<strong>on</strong>g>of</str<strong>on</strong>g> the morally relevant features is<br />

a master property, nor whether a c<strong>on</strong>sequentialist, a de<strong>on</strong>tological or a hybrid approach is the most<br />

appropriate framework for deciding whether or not a specific, or any, type <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g> is acceptable.<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g> Working Party has therefore not been able to agree <strong>on</strong> a single ethical stance. Instead, we present<br />

an outline <str<strong>on</strong>g>of</str<strong>on</strong>g> four possible ethical positi<strong>on</strong>s that can be taken, which mark positi<strong>on</strong>s <strong>on</strong> a c<strong>on</strong>tinuum:<br />

■ <str<strong>on</strong>g>The</str<strong>on</strong>g> ‘anything goes’ view (paragraphs 14.16–14.20)<br />

If humans see value in <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g>, then it requires no further ethical<br />

justificati<strong>on</strong> (no member <str<strong>on</strong>g>of</str<strong>on</strong>g> the Working Party takes this positi<strong>on</strong>).<br />

■ <str<strong>on</strong>g>The</str<strong>on</strong>g> ‘<strong>on</strong> balance justificati<strong>on</strong>’ view (paragraphs 14.2–14.27)<br />

In accepting <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> <strong>on</strong>e acts with full moral justificati<strong>on</strong>, while accepting<br />

that every reas<strong>on</strong>able step must be taken to reduce the costs that fall <strong>on</strong> <str<strong>on</strong>g>animals</str<strong>on</strong>g>.<br />

■ <str<strong>on</strong>g>The</str<strong>on</strong>g> ‘moral dilemma’ view (paragraphs 14.28–14.40)<br />

Most forms <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> pose moral dilemmas: however <strong>on</strong>e decides to act,<br />

<strong>on</strong>e acts wr<strong>on</strong>gly, either by neglecting human health and welfare or by harming <str<strong>on</strong>g>animals</str<strong>on</strong>g>.<br />

■ <str<strong>on</strong>g>The</str<strong>on</strong>g> ‘aboliti<strong>on</strong>ist’ view (paragraphs 14.41–14.52)<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g>re is no moral justificati<strong>on</strong> for any harmful <str<strong>on</strong>g>research</str<strong>on</strong>g> <strong>on</strong> sentient <str<strong>on</strong>g>animals</str<strong>on</strong>g> that is not to their<br />

benefit. Humans experiment <strong>on</strong> <str<strong>on</strong>g>animals</str<strong>on</strong>g> not because it is right but because they can (the<br />

‘weakness <str<strong>on</strong>g>of</str<strong>on</strong>g> morality’ view, as a sub-category <str<strong>on</strong>g>of</str<strong>on</strong>g> the aboliti<strong>on</strong>ist view, is c<strong>on</strong>sidered in<br />

paragraphs 14.52).<br />

For each positi<strong>on</strong> we describe (i) the justificati<strong>on</strong> for using <str<strong>on</strong>g>animals</str<strong>on</strong>g> in <str<strong>on</strong>g>research</str<strong>on</strong>g>, (ii) the implicati<strong>on</strong>s<br />

for using <str<strong>on</strong>g>animals</str<strong>on</strong>g> in <str<strong>on</strong>g>research</str<strong>on</strong>g> and in other c<strong>on</strong>texts, (iii) the value attributed to <str<strong>on</strong>g>research</str<strong>on</strong>g> and (iv)<br />

the role <str<strong>on</strong>g>of</str<strong>on</strong>g> the Three Rs. <str<strong>on</strong>g>The</str<strong>on</strong>g> reader is invited to judge whether <strong>on</strong>e or other <str<strong>on</strong>g>of</str<strong>on</strong>g> the positi<strong>on</strong>s is<br />

superior to others. In presenting them, we are clear that moral frameworks are not to be acquired<br />

and maintained in a simple ‘pick and choose’ fashi<strong>on</strong>. Rather, they require c<strong>on</strong>tinuous scrutiny<br />

and justificati<strong>on</strong> (paragraph 14.10).<br />

Furthermore, all members agree that independently <str<strong>on</strong>g>of</str<strong>on</strong>g> morally relevant features such as<br />

sentience, higher cognitive capacities, capability for flourishing and sociability, the acceptance <str<strong>on</strong>g>of</str<strong>on</strong>g><br />

even relatively mild experiments for great benefit depends <strong>on</strong> the acceptance <str<strong>on</strong>g>of</str<strong>on</strong>g> two vital moral<br />

assumpti<strong>on</strong>s: that the life <str<strong>on</strong>g>of</str<strong>on</strong>g> laboratory <str<strong>on</strong>g>animals</str<strong>on</strong>g> such as mice does not have absolute value; and<br />

that forced c<strong>on</strong>sequentialist sacrifice is acceptable. (By the latter term we mean to say that <strong>on</strong>e<br />

is able to justify a morally unequal distributi<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> costs and benefits am<strong>on</strong>g different beings.)<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g>re is no c<strong>on</strong>sensus within the Working Party as to whether these assumpti<strong>on</strong>s are morally<br />

acceptable. However, all members do agree with the c<strong>on</strong>diti<strong>on</strong>al: harmful <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>involving</str<strong>on</strong>g><br />

<str<strong>on</strong>g>animals</str<strong>on</strong>g> must be morally unacceptable if animal life is seen as having absolute value, or if forced<br />

c<strong>on</strong>sequentialist sacrifice is always seen as wr<strong>on</strong>g (paragraph 14.6).<br />

Public policy in the c<strong>on</strong>text <str<strong>on</strong>g>of</str<strong>on</strong>g> moral disagreement<br />

As in the case <str<strong>on</strong>g>of</str<strong>on</strong>g> other ethically c<strong>on</strong>tentious issues, such as aborti<strong>on</strong> or euthanasia, any society<br />

needs to settle <strong>on</strong> a single policy for practical purposes. Steps need to be taken to reduce as far<br />

as possible existing disagreement. At the very least, if a public policy is adopted that many believe<br />

to be morally wr<strong>on</strong>g, it may lead to instability, protest and, in extreme cases, civil unrest.<br />

XXIV

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