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The ethics of research involving animals - Nuffield Council on ...

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T h e e t h i c s o f r e s e a r c h i n v o l v i n g a n i m a l s<br />

and processes. In this c<strong>on</strong>text, two resp<strong>on</strong>dents to the C<strong>on</strong>sultati<strong>on</strong> commented as follows:<br />

‘It may well be that we can make significant improvements to the well-being <str<strong>on</strong>g>of</str<strong>on</strong>g> lab<br />

<str<strong>on</strong>g>animals</str<strong>on</strong>g> by making relatively simple modificati<strong>on</strong>s to standard husbandry practice.<br />

However, it is important not to be too anthropomorphic about what we c<strong>on</strong>ceive as<br />

quality <str<strong>on</strong>g>of</str<strong>on</strong>g> life for other <str<strong>on</strong>g>animals</str<strong>on</strong>g>, and what we do should be informed by more <str<strong>on</strong>g>research</str<strong>on</strong>g><br />

into animal behaviour and cogniti<strong>on</strong>.’<br />

Pr<str<strong>on</strong>g>of</str<strong>on</strong>g>essor Julian Blow<br />

‘Many schemes are available for scoring welfare and/or suffering in laboratory <str<strong>on</strong>g>animals</str<strong>on</strong>g>,<br />

and they can undoubtedly be useful. However, what is really needed is a comm<strong>on</strong>sense<br />

approach. Nobody who has lived with dogs and cats can fail to know when they are<br />

suffering, whether or not we could quantify it or describe it perfectly. We must not let<br />

those who want to apply experimental procedures to <str<strong>on</strong>g>animals</str<strong>on</strong>g> get away with clever and<br />

pseudoscientific arguments about animal c<strong>on</strong>sciousness, ability to perceive pain, etc., as<br />

a means <str<strong>on</strong>g>of</str<strong>on</strong>g> escaping the need to justify what they want to do.’<br />

Pr<str<strong>on</strong>g>of</str<strong>on</strong>g>essor Michael Balls, Chairman <str<strong>on</strong>g>of</str<strong>on</strong>g> the FRAME Trustees<br />

We c<strong>on</strong>clude that judgements based <strong>on</strong> scientific evidence, and those based <strong>on</strong> empathy must<br />

be taken into c<strong>on</strong>siderati<strong>on</strong> in assessments <str<strong>on</strong>g>of</str<strong>on</strong>g> animal welfare. Undue anthropomorphism, and<br />

the viewing <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> as mere <str<strong>on</strong>g>research</str<strong>on</strong>g> tools are equally inappropriate. We return to the<br />

ethical arguments about animal <str<strong>on</strong>g>research</str<strong>on</strong>g> in Chapters 14 and 15 and now c<strong>on</strong>sider more specific<br />

aspects relating to possible sources <str<strong>on</strong>g>of</str<strong>on</strong>g> suffering <str<strong>on</strong>g>of</str<strong>on</strong>g> laboratory <str<strong>on</strong>g>animals</str<strong>on</strong>g>.<br />

Sources <str<strong>on</strong>g>of</str<strong>on</strong>g> harm for laboratory <str<strong>on</strong>g>animals</str<strong>on</strong>g><br />

4.31 <str<strong>on</strong>g>The</str<strong>on</strong>g> discussi<strong>on</strong> about pain, suffering and distress that <str<strong>on</strong>g>research</str<strong>on</strong>g> <str<strong>on</strong>g>animals</str<strong>on</strong>g> may experience is <str<strong>on</strong>g>of</str<strong>on</strong>g>ten<br />

focused <strong>on</strong> experimental procedures. Resp<strong>on</strong>dents to the C<strong>on</strong>sultati<strong>on</strong> also pointed out that:<br />

‘It is not <strong>on</strong>ly scientific procedures that can cause suffering to <str<strong>on</strong>g>animals</str<strong>on</strong>g>, but also the c<strong>on</strong>diti<strong>on</strong>s<br />

<str<strong>on</strong>g>of</str<strong>on</strong>g> their captivity. Many laboratory <str<strong>on</strong>g>animals</str<strong>on</strong>g> are kept in bare, sterile living c<strong>on</strong>diti<strong>on</strong>s…’<br />

<str<strong>on</strong>g>The</str<strong>on</strong>g> Dr Hadwen Trust for Humane Research<br />

‘Envir<strong>on</strong>mental factors…have a great impact <strong>on</strong> the laboratory animal throughout its<br />

entire life, not <strong>on</strong>ly during experiments.’<br />

Pr<str<strong>on</strong>g>of</str<strong>on</strong>g>essor Vera Baumans<br />

Animals may experience adverse physiological and psychological states that can result from<br />

a range <str<strong>on</strong>g>of</str<strong>on</strong>g> factors (Box 4.4). We now give systematic c<strong>on</strong>siderati<strong>on</strong> to a number <str<strong>on</strong>g>of</str<strong>on</strong>g> areas that<br />

influence an animal’s welfare independent <str<strong>on</strong>g>of</str<strong>on</strong>g>, or in additi<strong>on</strong> to, specific experimental<br />

procedures. <str<strong>on</strong>g>The</str<strong>on</strong>g>se include:<br />

■ breeding (including the use <str<strong>on</strong>g>of</str<strong>on</strong>g> wild-caught <str<strong>on</strong>g>animals</str<strong>on</strong>g>);<br />

■ transportati<strong>on</strong>;<br />

■ housing;<br />

■ husbandry and care;<br />

■ handling;<br />

■ restraint;<br />

■ identificati<strong>on</strong>;<br />

■ any adverse effects <str<strong>on</strong>g>of</str<strong>on</strong>g> the procedures (e.g. nausea from toxic compounds, discomfort and<br />

pain from induced syndromes, natural and experimental infecti<strong>on</strong>s); and<br />

■ euthanasia.<br />

CHAPTER 4 THE CAPACITY OF ANIMALS TO EXPERIENCE PAIN, DISTRESS AND SUFFERING<br />

73

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