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NAVMED P-5010-8 - Navy Medicine - U.S. Navy

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8-29 CHAPTER 8. NAVY ENTOMOLOGY AND PEST CONTROL TECHNOLOGY 8-31<br />

(2) Children. Give atropine sulfate in<br />

proportion to body weight, approximately 0.05<br />

mg/kg.<br />

(3) Support therapy. 2-PAM<br />

(Pralidoxime Chloride or Protopam Chloride).<br />

(a) Adult dose – 1 gm IV slowly.<br />

(b) Infant dose – 250 mg IV slowly.<br />

Note. Contraindicated treatment compounds<br />

include: aminophylline, barbituates, morphine,<br />

phenothiazine tranquilizers, theophylline, or any<br />

respiratory depressant.<br />

8-30. Carbamate Pesticide Poisoning and<br />

Suggestions For Treatment<br />

a. Commonly used pesticides that exhibit<br />

reversible cholinesterase inhibition include<br />

carbaryl, dimetilan, and propoxur.<br />

b. Signs and symptoms of poisoning<br />

include pupillary constriction, salivation,<br />

profuse sweating, lassitude, loss of muscle<br />

coordination, nausea, vomiting, diarrhea,<br />

epigastric pain, and tightness in chest.<br />

c. Antidote<br />

(1) Adults. After cyanosis is<br />

overcome, give 2 to 4 mg of atropine sulfate IV.<br />

Repeat doses at 5 to 10 minute intervals until<br />

signs of atropinization appear. Maintain<br />

treatment for 24 hours or longer if necessary.<br />

8-31. Organochlorine Pesticide Poisoning<br />

and Suggestions For Treatment<br />

a. Organochlorine pesticides are central<br />

nervous system depressant/stimulants. They<br />

include benzene hexachloride (BHC), chlordane,<br />

DDT, dieldrin, heptachlor, and lindane. The<br />

exact mode of actions of these chemicals is not<br />

known. In general they act on the central<br />

nervous system to stimulate or depress, varying<br />

by compound. Repeated doses may affect liver<br />

and kidney functions.<br />

b. Signs and symptoms. Within 20<br />

minutes to 4 hours, the following may occur:<br />

headache, nausea, vomiting, restlessness, tremor,<br />

apprehension, convulsions, coma, respiratory<br />

failure, and death. Do not induce vomiting if the<br />

ingested poison is principally an organic solvent<br />

(e.g., kerosene).<br />

c. Treatment<br />

(1) Lavage stomach with 2-4 liters of tap<br />

water. Induce catharsis with 30 gm sodium<br />

sulphate in 1 cup of water.<br />

(2) Administer barbituates in appropriate<br />

doses repeated as necessary for restlessness or<br />

convulsions.<br />

(3) Avoid oils, oil laxatives, and<br />

epinephrine (adrenalin). Do not give stimulants.<br />

(4) Give calcium gluconate (10% in 10 ml<br />

ampules) IV every 4 hours.<br />

(2) Children. Give atropine sulfate in<br />

proportion to body weight, approximately 0.05<br />

mg/kg IV.<br />

Note. 2-PAM is contraindicated in carbamate<br />

insecticide poisoning. Also avoid aminophylline,<br />

barbiturates morphine, phenothiazine,<br />

tranquilizers, and theophylline.<br />

9 Nov 2004<br />

8-27

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